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A Pilot Study of Microbiome in Patients With Autism Spectrum Disorder and Their Unaffected Siblings

NCT05038748 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2021-09-16

No results posted yet for this study

Summary

The primary aims are to identify important gut microbiota signatures for youth with ASD, to identify dysbiosis features for different levels of ASD features and clinical courses, to search the possibility to intervene the disease course if we can tease out the dysbiosis responsible for the flare-up and improvement of the symptoms of the disease. The secondary aims are to identify the clinical and neuropsychological measures that are associated with direct and indirect regulation or interactions from gut-brain axis signaling, and based our preliminary results on reducing the measures for future large-scale microbiome study in ASD.

Conditions

Interventions

OTHER

Psychiatric diagnosis

Kiddie Schedule for Affective Disorders \& Schizophrenia (K-SADS) for DSM-5

OTHER

ASD diagnosis

Autism Diagnostic Interview-revised (ADI-R) and Autism Diagnostic Observation Scale (ADOS)

Sponsors & Collaborators

  • National Taiwan University Hospital

    lead OTHER

Eligibility

Min Age
7 Years
Max Age
25 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-01
Primary Completion
2020-12-31
Completion
2020-12-31

Countries

  • Taiwan

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05038748 on ClinicalTrials.gov