Prophylactic Norepinephrine and Phenylephrine Infusion for Hemodynamic Effects in Patients With Preeclampsia
NCT05035498 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 72
Last updated 2024-02-02
Summary
The purpose of this study is to investigate the maternal cardiac output response to prophylactic norepinephrine and phenylephrine infusion for postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
Conditions
- Hemodynamic Instability
Interventions
- DRUG
-
Phenylephrine
A maintenance dose of phenylephrine (0.625 μg/kg/min) infusion simultaneous with subarachnoid block
- DRUG
-
Norepinephrine
A maintenance dose of norepinephrine (0.05 μg/kg/min) infusion simultaneous with subarachnoid block
Sponsors & Collaborators
-
General Hospital of Ningxia Medical University
lead OTHER
Principal Investigators
-
Xinli Ni, Dr. · General Hospital of Ningxia Medical University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-02-01
- Primary Completion
- 2025-04-21
- Completion
- 2025-04-21
Countries
- China
Study Locations
More Related Trials
-
Prophylactic Norepinephrine and Phenylephrine Boluses for Postspinal Anesthesia Hypotension
NCT05035888 ·Status: COMPLETED ·Phase: NA
-
ED90 of Norepinephrine and Phenylephrine Infusions in Preeclamptic Patients
NCT06158022 ·Status: COMPLETED ·Phase: NA
-
ED90 of Norepinephrine and Phenylephrine Infusions Under Intensive Treatment
NCT06158048 ·Status: COMPLETED ·Phase: NA
-
Norepinephrine and Phenylephrine for Spinal Anesthesia-induced Hypotension.
NCT06508359 ·Status: COMPLETED ·Phase: NA
-
90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment
NCT06151522 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients
NCT06151470 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment in Preeclamptic Patients
NCT06158035 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Norepinephrine vs. Phenylephrine for Spinal Hypotension in Cesarean Section
NCT07153601 ·Status: COMPLETED ·Phase: NA
-
Norepinephrine on Maternal Hypotension After Combined Lumbar and Epidural Anaesthesia
NCT06498115 ·Status: RECRUITING ·Phase: PHASE4
-
Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
NCT00458003 ·Status: COMPLETED ·Phase: NA
-
Phenylephrine Versus Norepinephrine for Maintenance of Hemodynamic During Cesarean Section Under Spinal Anesthesia
NCT03849508 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Norepinephrine and Ephedrine on Hypotension After Spinal Anesthesia in Parturients
NCT02542748 ·Status: COMPLETED ·Phase: NA
-
Norepinephrine or Phenylephrine in Bolus for Hypotension in Cesarean Delivery
NCT03702400 ·Status: COMPLETED ·Phase: PHASE2
-
Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery
NCT02354833 ·Status: COMPLETED ·Phase: PHASE4
-
A Comparison of Intermittent Intravenous Boluses of Phenylephrine and Norepinephrine to Prevent Spinal-induced Hypotension in Cesarean Deliveries
NCT02962986 ·Status: COMPLETED ·Phase: NA
-
Ideal Dose of Phenylephrine to Treat Low Blood Pressure During Cesarean Section
NCT00379691 ·Status: COMPLETED ·Phase: NA
-
The Phenylephrine vs. Norepinephrine Infusion Undergoing Cesarean Section
NCT03833895 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Norepinephrine and Phenylephrine for Maternal Cardiac Output During Spinal Anesthesia for Elective Cesarean Delivery
NCT02969239 ·Status: UNKNOWN ·Phase: PHASE4
-
Intravenous Bolus of Phenylephrine vs. Norepinephrine in Preventing Hypotension After Spinal Anesthesia
NCT02854787 ·Status: COMPLETED ·Phase: PHASE4
-
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension
NCT04272567 ·Status: COMPLETED ·Phase: NA
-
ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment
NCT06158009 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section
NCT04404946 ·Status: COMPLETED ·Phase: NA
-
Norepinephrine Versus Phenylephrine Continuous Variable Infusion in Cesarean Delivery
NCT03328533 ·Status: COMPLETED ·Phase: PHASE4
-
Prevention of Hypotension During Cesarean Section
NCT03842046 ·Status: COMPLETED ·Phase: NA
-
Intramuscular Phenylephrine HCL for Prevention of Spinal Anesthesia Induced Hypotension
NCT05348980 ·Status: COMPLETED ·Phase: PHASE4