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Mitochondria Preservation by Exercise Training: a Targeted Therapy for Cancer and Chemotherapy-induced Cachexia

NCT05028192 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 144

Last updated 2021-09-29

No results posted yet for this study

Summary

This study aims to define the contribution of cancer and chemotherapy to muscle and systemic alterations that drive the onset of cachexia in rectal cancer patients and validate in human cancer cachexia (CC) the alterations in mitochondrial function and neuromuscular junction (NMJ) observed in the experimental models, thus providing the rationale for potential anti-cachexia strategies based on exercise and or exercise mimetics.

Conditions

Interventions

OTHER

no intervention

no intervention

Sponsors & Collaborators

  • University of Padova

    collaborator OTHER

  • Catholic University of the Sacred Heart

    collaborator OTHER

  • University of Roma La Sapienza

    collaborator OTHER

  • University of Turin, Italy

    lead OTHER

Principal Investigators

  • Maurizio Degiuli, Prof. · Università degli studi di Torino- Surgical Oncology and Digestive Surgery

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-27
Primary Completion
2024-09-01
Completion
2024-09-01

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05028192 on ClinicalTrials.gov