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Long-term Follow-up of Subjects Treated With CAR T Cells

NCT05024175 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2026-03-16

No results posted yet for this study

Summary

This is a single site, non-randomized, open-label, long-term safety and efficacy follow-up study for Phase 1 studies that evaluate the safety and efficacy of CAR T cells: NCT05660369 (DF/HCC# 22-175) and NCT06026319 (DF/HCC# 23-474).

Conditions

  • Long Term Adverse Effects
  • CAR-T
  • Duty to Follow Up
  • Adult
  • Progression-Free Survival
  • Disease-Free Survival
  • Overall Survival

Interventions

DIAGNOSTIC_TEST

Disease assessments

CT (Computerized Tomography) scan or PET-CT (Positron Emission Tomography-Computerized Tomography) scans as per protocol

PROCEDURE

Tumor Biopsy

Tumor Biopsy per protocol

DIAGNOSTIC_TEST

Blood test

Blood Test per protocol

Sponsors & Collaborators

  • Marcela V. Maus, M.D.,Ph.D.

    lead OTHER

Principal Investigators

  • Matthew J Frigault, MD · Massachusetts General Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-08-07
Primary Completion
2038-08-01
Completion
2039-08-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05024175 on ClinicalTrials.gov