Efficacy and Safety of Immunotherapy in Non-small Cell Lung Cancer With Uncommon Histological Type
NCT05023837 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2022-01-25
Summary
This study was designed to explore the efficacy and safety of immune checkpoint inhibitor for advanced uncommon pathological types of lung cancer whether or not it is accompanied by a driver mutationin the real world. Through retrospective collection of clinical data of patients with uncommon pathological types of lung cancer.The patients who are treated with immunosuppressive agents are screened out, and they are divided into immune combination therapy or immune monotherapy, and further evaluate whether there is a difference in efficacy between the two.
Conditions
- Uncommon Pathological Types of Lung Cancer
Interventions
- DRUG
-
Pembrolizumab 100 MG Injection
Pembrolizumab iv 200mg q21d
Sponsors & Collaborators
-
Hunan Province Tumor Hospital
lead OTHER
Principal Investigators
-
Yongchang Zhang, MD · Hunan Cancer Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-03-02
- Primary Completion
- 2021-08-02
- Completion
- 2021-08-03
Countries
- China
Study Locations
More Related Trials
-
Real World Observational Study of Pembrolizumab for Chinese Advanced NSCLC
NCT04153097 ·Status: UNKNOWN
-
Neoadjuvant Immune Checkpoint Inhibitor Combined With Chemotherapy in Non-small Cell Lung Cancer
NCT04945200 ·Status: UNKNOWN
-
The Efficacy and Safety of Adjuvant Immunotherapy After Pathological Complete Response Following Neoadjuvant Chemoimmunotherapy in Patients with Resectable NSCLC
NCT06243679 ·Status: ACTIVE_NOT_RECRUITING
-
Atezolizumab Plus Bevacizumab and Chemotherapy in First-Line Metastatic Nonsquamous NSCLC
NCT05261438 ·Status: COMPLETED
-
Efficacy and Safety of Conventional and Low-dose Platinum Gemcitabine Combined With Cindilimab With Delayed Administration in First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer
NCT05312840 ·Status: UNKNOWN ·Phase: PHASE4
-
The Efficacy and Safety of the Bispecific Anti-PD-1/PD-L1 Antibody IBI318 Combined with Lenvatinib in NSCLC.
NCT04777084 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy, Safety, and Pharmacodynamics of Tislelizumab Monotherapy and Multiple Tislelizumab-based Immunotherapy Combinations in Participants With Resectable Non-Small Cell Lung Cancer
NCT05577702 ·Status: COMPLETED ·Phase: PHASE2
-
Real-world Association Between Concomitant Beta-blocker Exposure and Anti-PD-1/PD-L1 Treatment Outcomes in Advanced Non-Small Cell Lung Cancer
NCT05387512 ·Status: COMPLETED
-
A Study of Anti-PD1 Antibody-activated TILs in Non-small Cell Lung Cancer
NCT03903887 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
An Open-label, Single-arm Clinical Study of Stapokibart Injection in Combination with Tislelizumab Injection in Patients with Non-Small Cell Lung Cancer
NCT06883552 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Immune Indicator Model for Predicting Efficacy of PD-1 Monoclonal Antibody
NCT05392413 ·Status: RECRUITING
-
Predictive Biomarker for Efficacy and Safety of Combination of Chemotherapy and Tislelizumab in NSCLC
NCT05244837 ·Status: UNKNOWN ·Phase: PHASE2
-
The Therapeutic Effect of Immunotherapy in Patients With Advanced Lung Squamous Carcinoma
NCT06647836 ·Status: ENROLLING_BY_INVITATION
-
Envafolimab as First-line Treatment of Aged Patients in Advanced NSCLC
NCT05055167 ·Status: UNKNOWN ·Phase: PHASE2
-
Exploration of Immunodynamic Monitoring in the Population Evaluation of Neoadjuvant Chemotherapy Immunotherapy in Patients With Solid Tumors of the Chest.
NCT05044728 ·Status: UNKNOWN ·Phase: PHASE2
-
Risk Factors and Long-term Impact of ICIs
NCT05754983 ·Status: ACTIVE_NOT_RECRUITING
-
Investigating the Biomarkers in Tumor and Peripheral Blood to Evaluate the Efficacy of Cancer Immunotherapy in Chest Cancer Patients
NCT05789498 ·Status: UNKNOWN
-
Umbrella Biomarker-Guided Therapy in NPC
NCT04605562 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Evaluating the Safety and Efficacy of Pembrolizumab Combined With MWA for Advanced NSCLC
NCT03769129 ·Status: RECRUITING ·Phase: NA
-
Efficacy and Safety of IBI351 in Combination With Chemotherapy in Advanced Non-squamous Non-small Cell Lung Cancer Subjects With KRAS G12C Mutation
NCT05504278 ·Status: RECRUITING ·Phase: PHASE1
-
Efficacy and Biomarker Explanation of IBI-322 Plus Lenvatinib on Extensive Stage Small Cell Lung Cancer
NCT05296603 ·Status: RECRUITING ·Phase: PHASE2
-
Investigating the Biomarkers in Tumor and Peripheral Blood to Evaluate the Efficacy of Cancer Immunotherapy in Chest Cancer Patients
NCT06790797 ·Status: RECRUITING
-
COVID-19 Vaccine Effectiveness Against Recurrent Infection Among Lung Cancer Patients and Biomarker Research
NCT06168032 ·Status: RECRUITING ·Phase: NA
-
Efficacy and Safety of Use of Platinum Based Doublet Chemotherapy Plus Antiangiogenesis and Immune Checkpoint Inhibitors in Patients With Advanced Non-squamous Non-small Cell Lung Cancer
NCT04137588 ·Status: UNKNOWN
-
Camrelizumab With Chemotherapy in Adults With Medically Inoperable Early Stage NSCLC
NCT04530227 ·Status: RECRUITING ·Phase: PHASE2