MedTrace Logo

Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients

NCT05019209 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2024-10-15

No results posted yet for this study

Summary

The present study investigates the reaction of the skin upon exposure to house dust mite (HDM) in patients with atopic dermatitis who have antibodies against HDM in the blood. A further aim is to assess nasal symptoms after exposure to HDM in an allergen challenge chamber and compare the results with data from previous studies.

Conditions

Interventions

DRUG

House Dust Mite Allergen

D. pteronyssinus lyophilisate dissolved in 5% sodium chloride solution, spray dried

OTHER

Allergen-free air

No allergen added to room ventilation of allergen challenge chamber

Sponsors & Collaborators

  • Hannover Medical School

    collaborator OTHER

  • Fraunhofer-Institute of Toxicology and Experimental Medicine

    lead OTHER

Principal Investigators

  • Jens M Hohlfeld, Prof. Dr. · Fraunhofer ITEM

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-10
Primary Completion
2022-02-14
Completion
2022-02-14

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05019209 on ClinicalTrials.gov