Neuroendocrine Neoplasms Methylation Based Classifier - The NEMESIs-study
NCT05013957 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 32
Last updated 2025-01-29
Summary
Neuroendocrine neoplasms (NEN) are rare tumors that mainly occur in the gastrointestinal tract and the lungs. The currently available diagnostic and prognostic markers do not adequately represent the diversity of these tumors. Methylation analyzes of the tumor DNA represent a new, promising approach.
The aim of this project is therefore to improve the diagnostic and prognostic evaluation of neuroendocrine neoplasms by means of methylation analysis of the tumor DNA. On the one hand, existing tumor samples from the biobank of Basel University Hospital are evaluated, on the other hand, patients who are undergoing an operation will be prospectively inquired
Conditions
Interventions
- DIAGNOSTIC_TEST
-
Methylation analysis
Methylation analysis
Sponsors & Collaborators
-
University Hospital, Basel, Switzerland
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-01-01
- Primary Completion
- 2024-12-30
- Completion
- 2024-12-30
Countries
- Switzerland
Study Locations
More Related Trials
-
Collection of Liquid Biopsy Samples of Neuroendocrine Neoplasms (NEN) Patients - Collection of NET (CollectNET) 2.0, a Study by the BE-FORCE Consortium
NCT06541080 ·Status: RECRUITING
-
Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer
NCT01109420 ·Status: RECRUITING
-
Genetic Analysis of Brain Tumors
NCT00031538 ·Status: TERMINATED
-
Dissecting the Mechanism of DNA Methylation on the Invasiveness of Pituitary Tumors.
NCT05634655 ·Status: UNKNOWN
-
EpigenOMic Determinants of the Neuroendocrine Phenotype As Biomarkers for Neuroendocrine Neoplasms
NCT06785597 ·Status: RECRUITING
-
Evaluation of Blood Vessel Formation in Endocrine Tumors
NCT00923780 ·Status: COMPLETED
-
Prediction of True Oligo-metastatic Disease.
NCT05806151 ·Status: RECRUITING
-
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
NCT01005654 ·Status: RECRUITING
-
Clinical Utility Assay as a Biomarker for Gastroenteropancreatic and Lung Neuroendocrine Tumors
NCT02948946 ·Status: COMPLETED
-
Identification of Biomarker Profiles GEP-NEN Patients
NCT02838862 ·Status: UNKNOWN
-
Plasma cfDNA Fragmentomics for Early pNET Detection and Differential Diagnosis of Solid Pancreatic Tumors
NCT05847855 ·Status: RECRUITING
-
National Study of Adrenal Tumours
NCT06870396 ·Status: ENROLLING_BY_INVITATION
-
Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
NCT01950572 ·Status: RECRUITING
-
Type 1 Multiple Endocrine Neoplasia Cohort Study
NCT03262129 ·Status: UNKNOWN
-
Multicenter Retrospective Database on Prognostic and Predictive Factors in Patients With Neuroendocrine Tumors
NCT05168631 ·Status: ACTIVE_NOT_RECRUITING
-
IDEntification of New Predisposition Genes in Differentiated THYroid Cancer
NCT05014698 ·Status: TERMINATED ·Phase: NA
-
Natural History and Tissue Acquisition Study of Adrenocortical Carcinoma
NCT02015026 ·Status: COMPLETED
-
Registry on NEN Patients and COVID-19
NCT04444401 ·Status: UNKNOWN
-
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome
NCT04431024 ·Status: RECRUITING
-
Impact of O6-methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation and MGMT Expression on Dacarbazine Treated Sarcoma Patients (MGMT)
NCT04893356 ·Status: ACTIVE_NOT_RECRUITING
-
Implementation of the Methylome in the Characterization of Solid Tumors
NCT07268066 ·Status: RECRUITING
-
Rare CNS Tumors Outcomes &Risk
NCT03251989 ·Status: COMPLETED
-
Genetic Evaluation of Families With Endocrine Cancers
NCT01794676 ·Status: COMPLETED
-
DNA Tests in Detecting Disseminated Disease in Tumor, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma
NCT01419509 ·Status: COMPLETED
-
Optimal Methods of Disease Progression and Survival Analysis in Children and Adults Patients With Adrenocortical Cancer (ACC)
NCT04358107 ·Status: ACTIVE_NOT_RECRUITING