Using Explainable AI Risk Predictions to Nudge Influenza Vaccine Uptake

Summary

The study team previously demonstrated that patients are more likely to receive flu vaccine after learning that they are at high risk for flu complications. Building on this past work, the present study will explore whether providing reasons that patients are considered high risk for flu complications (a) further increases the likelihood they will receive flu vaccine and (b) decreases the likelihood that they receive diagnoses of flu and/or flu-like symptoms in the ensuing flu season. It will also examine whether informing patients that their high-risk status was determined by analyzing their medical records or by an artificial intelligence (AI) / machine-learning (ML) algorithm analyzing their medical records will affect the likelihood of receiving the flu vaccine or diagnoses of flu and/or flu-like symptoms.

Conditions

• Influenza
• Vaccination
• Health Promotion
• Health Behavior
• Risk Reduction

Interventions

BEHAVIORAL

Algorithm-based recommendation

Mailed letter, SMS, and/or patient portal message

BEHAVIORAL

Reminder

Mailed letter, short message service (SMS) text, and/or patient portal message

BEHAVIORAL

Risk reduction

Mailed letter, SMS, and/or patient portal message

BEHAVIORAL

Medical records-based recommendation

Mailed letter, SMS, and/or patient portal message

Sponsors & Collaborators

• Geisinger Clinic

  collaborator OTHER

• Massachusetts Institute of Technology

  collaborator OTHER

• National Institute on Aging (NIA)

  collaborator NIH

• National Bureau of Economic Research, Inc.

  lead OTHER

Principal Investigators

• Michelle N Meyer, PhD JD · Geisinger Clinic

• Christopher F Chabris, PhD · Geisinger Clinic

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-09-09

Primary Completion

2021-11-05

Completion

2022-07-31

Countries

• United States

Study Locations