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Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study

NCT04996706 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 21000

Last updated 2026-02-27

No results posted yet for this study

Summary

The goal of this infrastructure protocol is to build and maintain a large and diverse observational cohort study to support broad and cutting-edge research focused on NHL prognosis and survivorship. The LEO cohort will promote identification of clinical (including co-morbid diseases), epidemiologic (including lifestyle and other exposures), host genetic, tumor, and treatment factors that impact multiple outcomes (including event-free, overall and lymphoma-specific survival; new onset comorbidities; and patient-reported outcomes). This resource also will allow examination of the interaction among these factors in order to better understand the clinical and molecular epidemiology of outcomes in NHL. Ultimately, this approach will drive discovery and validation of treatment endpoints, improve prognostication, and identify novel approaches to improve short and long-term outcomes for NHL patients.

Conditions

  • Lymphoma, Non-Hodgkin

Sponsors & Collaborators

  • Emory University

    collaborator OTHER

  • University of Iowa

    collaborator OTHER

  • M.D. Anderson Cancer Center

    collaborator OTHER

  • Washington University School of Medicine

    collaborator OTHER

  • University of Rochester

    collaborator OTHER

  • Weill Medical College of Cornell University

    collaborator OTHER

  • University of Miami

    collaborator OTHER

  • National Cancer Institute (NCI)

    collaborator NIH

  • Mayo Clinic

    lead OTHER

Principal Investigators

  • James R Cerhan, MD,PhD · Mayo Clinic

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-08-16
Primary Completion
2031-03-31
Completion
2031-03-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04996706 on ClinicalTrials.gov