Improving Diagnosis and Treatment of Metastatic Advanced Prostate Cancer
NCT04984395 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2021-07-30
Summary
The aim of this study is to provide clinical evidence to determine if Whole Body Magnetic Resonance Imaging (WBMRI) with a novel technique called diffusion-weighted imaging (DWI) can improve current treatment for APC patients, allowing for early identification of disease progression or treatment response, hence facilitating clinical decision-making and leading to improvement in patient care. The IDT study includes two retrospective analyses and a single centre prospective observational study for APC patients.
Conditions
- Advanced Prostate Carcinoma
Interventions
- DIAGNOSTIC_TEST
-
Post-treatment CT-guided bone marrow biopsy
At post-treatment, 12 +/- 3 weeks after initiating treatment, patients will undergo a CT guided bone marrow biopsy of the same lesion as baseline.
Sponsors & Collaborators
-
Royal Marsden NHS Foundation Trust
lead OTHER
Principal Investigators
-
Nina Tunariu · The Royal Marsden NHS FT
Eligibility
- Min Age
- 18 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-07-30
- Primary Completion
- 2024-05-31
- Completion
- 2024-05-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
Magnetic Resonance Imaging to Locate and Characterize Prostate Cancer
NCT00082147 ·Status: COMPLETED ·Phase: NA
-
Diffusion-Weighted MRI in Staging Patients With Localized Prostate Cancer
NCT02237612 ·Status: COMPLETED ·Phase: NA
-
MRI-guided Bone Marrow Biopsies of Prostate Cancer Patients
NCT00165386 ·Status: COMPLETED ·Phase: NA
-
Localising Occult Prostate Cancer Metastases With Advanced Imaging TEchniques
NCT02935816 ·Status: UNKNOWN
-
Non-contrast MR Imaging for Whole Body Cancer Detection and Characterization
NCT03440554 ·Status: UNKNOWN ·Phase: NA
-
Application of High Resolution Diffusion-weighted MR Imaging Pulse Sequence in Head and Neck, and Prostate Cancers
NCT01535898 ·Status: COMPLETED
-
uPAR PET/CT in Radium-223-dichloride Treatment of Patients With Metastatic Castration-resistant Prostate Cancer
NCT02964988 ·Status: TERMINATED ·Phase: PHASE2
-
Comparison of 5.0T and 3.0T Biparametric Magnetic Resonance Imaging in the Diagnosis of Prostate Cancer
NCT06612047 ·Status: RECRUITING
-
Diagnostic Imaging of Bone Metastases in Prostate Cancer Patients
NCT03134261 ·Status: UNKNOWN ·Phase: NA
-
Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer
NCT04692675 ·Status: RECRUITING ·Phase: NA
-
Multiparametric Whole-Body MRI: a Game Changer in Metastatic Prostate Cancer
NCT06827340 ·Status: COMPLETED
-
Optimization of Spectroscopic Imaging Parameters and Procedures for Prostate at 3 Tesla Using an External Probe
NCT00314535 ·Status: COMPLETED
-
Characterize Tumor Hypoxia by Magnetic Resonance Imaging
NCT03987568 ·Status: WITHDRAWN ·Phase: NA
-
Optimization of the Core Number and Location for Targeted Prostate Biopsy
NCT04983706 ·Status: UNKNOWN ·Phase: NA
-
Head-to-head Comparison of [18F]F-PSMA-N5 With [18F]F-PSMA-1007 PET/CT in PCa Diagnosis, Recurrence, and Metastasis
NCT06462495 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
WB-DW-MRI vs CHOLINE-PET/CT for Selecting Treatments in Recurrent Prostate Cancer
NCT02858128 ·Status: COMPLETED
-
MRI in Diagnosing Prostate Cancer
NCT01292291 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Treatment Response Using Multiparametric MRI After Prostate Radiotherapy
NCT02312401 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Phase II, Prospective Study of MRI in the Reclassification of Men Considering Active Surveillance in Prostate Cancer
NCT01858688 ·Status: COMPLETED ·Phase: NA
-
An Investigational Scan (MRI With Dixon Based Sequences) in Detecting Prostate Cancer
NCT05047965 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Prostate Cancer Monitoring Using [18F]DCFPyL and Blood Based Biomarkers
NCT03585114 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Defining the Extent and Grade of Prostate Cancer Using Dynamic Contrast Enhanced Diffusion Weighted and BOLD MRI
NCT00242112 ·Status: COMPLETED ·Phase: NA
-
Combined Prostate-specific Antigen, Multi-parametric MRI and Targeted Prostate Biopsy for Prostate Cancer Screening
NCT04322045 ·Status: UNKNOWN ·Phase: NA
-
Response Evaluation of Cancer Therapeutics in Metastatic Castration-Resistant Prostate Cancer to the Bone
NCT06321679 ·Status: RECRUITING
-
Early Changes In Multiparametric MRI In Prostate Cancer
NCT01959542 ·Status: COMPLETED ·Phase: NA