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Photobiomodulation Therapy in the Management of Hand-foot Syndrome and Hand-foot Skin Reaction

NCT04979078 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2023-06-18

No results posted yet for this study

Summary

Hand-foot syndrome (HFS) is a side effect of chemotherapy. HFS is characterized by redness, swelling, and pain on the palms of the hands and/or soles of the feet, which can progress to blistering. Hand-foot skin reaction (HFSR) refers to symptoms affecting the hands and/or feet associated with multikinase inhibitors (TKIs). HFS and HFSR are painful complications that can lead to compromised daily activities, sleep-wake disturbance and impaired mobility, eventually decreasing Quality of Life (QoL).

Photobiomodulation therapy (PBMT) is a non-invasive therapy based on the application of visible and/or near-infrared light produced by a laser diode or a light-emitting diode. The scientifically proven biologic effects of PBM are improved wound healing, and a reduction in pain, inflammation, and oedema. The aim of this study is to evaluate the effectiveness of PBMT in the management of HFS and HFSR.

Conditions

  • Hand-foot Syndrome
  • Hand-foot Skin Reaction

Interventions

DEVICE

Photobiomodulation therapy (PBMT)

Patients will receive PBM on the sole of their feet and palms of their hands

Sponsors & Collaborators

  • Hasselt University

    collaborator OTHER

  • Jessa Hospital

    lead OTHER

Principal Investigators

  • Jeroen Mebis, MD, PhD · Head of Medical Oncology Department

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-12
Primary Completion
2024-08-31
Completion
2029-08-31

Countries

  • Belgium

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04979078 on ClinicalTrials.gov