Men and Women With Different Designs and Semi-individual Total Knee Replacement

Summary

This study aims to evaluate the effectiveness of femoral condyle prosthesis, tibial tray prosthesis and meniscus prosthesis of semi-individualized total knee replacement prostheses designed with gender differences; and compare and analyze with the current classic prostheses, showing gender differences. The designed semi-personalized total knee replacement prosthesis lays the foundation for clinical application, including:

1. Compared with the classic osteotomy method, compare whether the semi-individualized total knee arthroplasty with a gender-specific design has advantages and better safety in the osteotomy method.
2. To evaluate the difference between the amount of osteotomy in the semi-individualized total knee arthroplasty designed for gender differences and the amount of classic osteotomy.
3. Compared with classic prostheses in the market, verify the clinical effects of semi-individualized total knee replacement prostheses designed for gender differences, and provide a basis for their clinical promotion and application.

Conditions

• Arthroplasty, Replacement, Knee

Interventions

PROCEDURE

semi-individualized total knee replacement treatment with a gender-specific design

Patients in the experimental group received a semi-individualized total knee replacement treatment with a gender-specific design.

PROCEDURE

Zimmer total knee replacement prostheses (Zimmer, Warsaw, IN, USA)

Patients in the control group received imported Zimmer total knee replacement prostheses (Zimmer, Warsaw, IN, USA).

Sponsors & Collaborators

• Guizhou Orthopedics Hospital

  collaborator UNKNOWN

• Shenyang Orthopedic Hospital

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Xi'an Honghui Hospital

  collaborator OTHER

• First Affiliated Hospital of Chongqing Medical University

  collaborator OTHER

• The Affiliated Hospital Of Guizhou Medical University

  collaborator OTHER

• Jining Medical University

  collaborator OTHER

• Northern Jiangsu People's Hospital

  collaborator OTHER

• Inner Mongolia People's Hospital

  collaborator OTHER

• Shenzhen Pingle Orthopedics Hospital

  collaborator UNKNOWN

• Peking University Third Hospital

  lead OTHER

Principal Investigators

• Jiakuo Yu, Doctor · Peking University Third Hospital

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-01-01

Primary Completion

2025-01-01

Completion

2025-01-01