Myeloid-derived Suppressor Cells in Colorectal Cancer
NCT04943419 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90
Last updated 2022-07-07
Summary
The aim of the study is to evaluate whether the preoperative level of myeloid-derived suppressor cells is associated with postoperative complications classified by Clavien-Dindo categories. Levels of all MDSC, polymorphonuclear MDSC (PMNMDSC), monocytic MDSC (MMDSC), early-stage MDSC (EMDSC) and monocytic to polymorphonuclear MDSC ratio (M/PMN MDCS) were established and compared in patients with postoperative complications, severe postoperative complications (\>= IIIA according to Clavien-Dindo) and severe septic complications.
Conditions
- Colorectal Cancer
- Suppression
- Complication,Postoperative
- Radiotherapy
Interventions
- DIAGNOSTIC_TEST
-
Level of Myeloid-Derived Suppressor Cells
Establishing of levels of all MDSC, PMNMDSC, MMDSC, EMDSC, M/PMN MDSC ratio on the day before operation.
Sponsors & Collaborators
-
Jagiellonian University
lead OTHER
Principal Investigators
-
Radoslaw Pach, Ph.D. · Jagiellonian University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-04-01
- Primary Completion
- 2021-02-27
- Completion
- 2021-06-21
Countries
- Poland
Study Locations
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