Evaluation of Heart Status in Patients of Beta Thalassemia Using Echocardiogram
NCT04929574 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1200
Last updated 2021-06-18
Summary
Heart failure from myocardial iron deposition is a severe complication for patients with transfusion-dependent beta thalassemia . Increased cardiac iron content impacts the contractility of cardiomyocytes and can also lead to myocarditis, pericarditis, and arrhythmias. The severity of cardiac dysfunction depends on the amount of iron deposited in the myocardium.Echocardiogram is used as noninvasive method to observe heart status. The objective of this study is to evaluate the heart status in patients of Beta Thalassemia from southern China.
Conditions
- Beta Thalassemia
Interventions
- DIAGNOSTIC_TEST
-
Echocardiogram and Hematological Analysis
Echocardiogram and Hematological Analysis
Sponsors & Collaborators
-
ZhuHai Hospital
collaborator OTHER -
Shenzhen Children's Hospital
collaborator OTHER_GOV -
Shenzhen Second People's Hospital
collaborator OTHER -
Jiangmen Maternity and Child Health Care Hospital
collaborator UNKNOWN -
Yongzhou Maternity and Child Health Hospital
collaborator UNKNOWN -
Nanfang Hospital, Southern Medical University
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-07-01
- Primary Completion
- 2024-07-01
- Completion
- 2025-12-30
Countries
- China
Study Locations
More Related Trials
-
Iron Deficiency in Patients With Heart Failure and Reduced and Mildly Reduced Ejection Fraction
NCT05992116 ·Status: COMPLETED
-
Effect of Aterial Stiffness on Myocardial Work in Patients With Hypertension
NCT04573257 ·Status: UNKNOWN
-
Impact of Iron Deficiency and Its Correction on Mitochondrial Metabolism of the Cardiomyocyte (MitoCardioFer)
NCT03541213 ·Status: COMPLETED ·Phase: NA
-
Echocardiographic Assessment of the Impact of Diabetes and Prognostic Analysis of Heart Transplantation
NCT04976517 ·Status: UNKNOWN
-
Prognostic Relevance of High-sensitivity Troponin in Patients With Acute Decompensated Heart Failure
NCT01429857 ·Status: COMPLETED
-
Clinical Comparison of Patients With Transthyretin Cardiac Amyloidosis and Patients With Heart Failure With Reduced Ejection Fraction
NCT05896904 ·Status: UNKNOWN ·Phase: NA
-
Investigation Into the Use of Ultrasound Technique in the Evaluation of Heart Disease
NCT00001632 ·Status: COMPLETED
-
Study of Myocardial Deformation Parameters in Patients With Hypertrophic Cardiomyopathy
NCT04112511 ·Status: COMPLETED
-
2D Speckle-tracking Echocardiography in Chemotherapy-induced Cardiomyopathy With Cardiovascular Risk Factors
NCT04547465 ·Status: UNKNOWN
-
Three-dimensional Assessment of Intraventricular Dyssynchrony Using Fast Dobutamine Gated SPECT
NCT02510677 ·Status: COMPLETED ·Phase: NA
-
Investigation of Heart Function in Patients With Heart Valve Defects
NCT00001314 ·Status: COMPLETED
-
Red Flags for Cardiac Examination for Early Detection of Congenital Heart Disease
NCT04801251 ·Status: UNKNOWN ·Phase: NA
-
Long-term Echocardiographic Findings in Takotsubo Syndrome
NCT05084157 ·Status: UNKNOWN
-
A Real-World Study on Hypertrophic Cardiomyopathy in Chinese Population
NCT06775665 ·Status: NOT_YET_RECRUITING
-
Predictive Factors and Consequences of Myocardial Fibrosis in Hypertrophic Cardiomyopathy
NCT02922517 ·Status: UNKNOWN
-
Contrast Echocardiography Cost Effectiveness for Left Ventricular Thrombus Assessment
NCT02555527 ·Status: COMPLETED
-
Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated Cardiomyopathy
NCT07293338 ·Status: RECRUITING
-
A Clinical Study of Immunoadsorption Therapy for Dilated Cardiomyopathy
NCT02915718 ·Status: COMPLETED ·Phase: NA
-
Observational Study for Patients With Hypertrophic Cardiomyopathy
NCT04851652 ·Status: RECRUITING
-
Prognostic Value of Right Ventricular Myocardial Strain in Patients With Acute Myocardial Infarction
NCT05404555 ·Status: UNKNOWN
-
Evaluation of Left Ventricular Function by Speckle Tracking Echocardiography in Patient Hospitalised in Intensive Care Unit for Vaso-occlusive Crisis
NCT04864041 ·Status: UNKNOWN
-
Evaluation of the Diagnostic Performance of Dynamic Myocardial Perfusion Scintigraphy in Comparison With Invasive Intracoronary FFR Measurement, in the Assessment of Significant Residual Coronary Stenosis After Acute Coronary Syndrome: Dyna-MI Pilot Study.
NCT05940285 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Stress Echo 2020 - The International Stress Echo Study
NCT03049995 ·Status: UNKNOWN
-
Effect of Cardiac Resynchronization Therapy (CRT) on Skeletal Muscle Histology, Neuroendocrine Activation and Inflammatory Response
NCT01019915 ·Status: COMPLETED ·Phase: PHASE4
-
The Role of Sympathetic Tone Regarding the Anatomical and Functional Recovery of the Left Ventricle in TakoTsubo Syndrome
NCT04695587 ·Status: UNKNOWN