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Insulin Stimulated Vasodilation in Patients With Type 2 Diabetes

NCT04907838 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2021-06-01

No results posted yet for this study

Summary

This study evaluates the role of endothelin in insulin stimulated vasodilation and glucose uptake. The subjects will complete an hyperinsulinemic euglycemic clamp with and without blockade of the endothelin receptors.

Conditions

  • Type2 Diabetes

Interventions

DRUG

Insulin clamp

Continous infusion insulin + glucose

DRUG

BQ123

Continuous infusion of Insulin + glucose + BQ123

DRUG

BQ123 + BQ788

Continous infusion of insulin + glucose + BQ123 + BQ788

Sponsors & Collaborators

  • The University of Texas at Arlington

    collaborator OTHER

  • University of Southern Denmark

    lead OTHER

Principal Investigators

  • Stefan Mortensen, DMSc · Professor

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-05-01
Primary Completion
2021-07-30
Completion
2021-07-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04907838 on ClinicalTrials.gov