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Is a Single Daily Session Combining HS + Physio Sufficient to Obtain Long-term Clinical Benefits in Bronchiectasis?

NCT04905992 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2021-06-18

No results posted yet for this study

Summary

The present study will aim to find out whether a home treatment in people with bronchiectasis consisting of a single daily session to facilitate expectoration (combining nebulization of hypertonic saline (HS) at 6% followed by airway clearance techniques) is at least as effective as performing two sessions per day following the same process in each of the sessions, during a period of 6 months.

Conditions

Interventions

OTHER

Hypertonic saline at 6%

Participants will start the sessions by inhaling a short-acting bronchodilator or an anticholinergic to avoid the presence of bronchospasm during nebulisation. The hypertonic solution (at 6%) will be administered through the Turbo Boy nebuliser (Pari®). The intervention will take place at home.

OTHER

Airway clearance techniques (oscillating positive expiratory pressure therapy)

Following nebulisation, participants will perform airway clearance techniques using an oscillating positive expiratory pressure device for at least 15 minutes. The intervention will take place at home

Sponsors & Collaborators

  • Hospital Clinic of Barcelona

    collaborator OTHER

  • Universidad San Jorge

    collaborator OTHER

  • Hospital Clínico Universitario Lozano Blesa

    lead OTHER

Principal Investigators

  • Victoria Alcaraz-Serrano · Hospital Clinic of Barcelona

  • Beatriz Herrero-Cortina · Hospital Clínico Universitario Lozano Blesa

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-07-01
Primary Completion
2023-06-30
Completion
2023-12-31

Countries

  • Spain

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04905992 on ClinicalTrials.gov