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Effectiveness of Zinc Supplementation With Topical Retinoids in Acne Vulgaris Patients

NCT04899843 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 122

Last updated 2022-03-21

No results posted yet for this study

Summary

The study was 8 weeks, randomized, double-blind, placebo-controlled trial to assess the effect of zinc sulphate on symptoms of mild and moderate acne vulgaris in 122 patients. Participants was assessed at baseline, and 8 weeks. Subjects was randomized to receive either 20 mg elemental zinc daily or 20 mg placebo tablet daily for 8 weeks. The primary outcome was the measure of the GAGS score and the secondary measure includes serum zinc level and evaluate adverse effects.

Conditions

  • Acne Vulgaris

Interventions

DIETARY_SUPPLEMENT

Zinc sulphate tablet 20 mg

Zinc sulphate tablet 20 mg daily orally for 8 weeks along with topical retinoids.

DIETARY_SUPPLEMENT

Placebo tablet 20 mg

Placebo tablet 20 mg daily orally for 8 weeks along with topical retinoids

Sponsors & Collaborators

  • Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

    lead OTHER

Principal Investigators

  • Prof. Md. Sayedur Rahman, MBBS, Mphil, FCPS · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
11 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-27
Primary Completion
2021-11-30
Completion
2021-11-30

Countries

  • Bangladesh

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04899843 on ClinicalTrials.gov