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Serological Response to mRNA and Inactivated COVID-19 Vaccine in Health Care Workers in Hong Kong

NCT04898946 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 480

Last updated 2024-02-28

No results posted yet for this study

Summary

Since the first local case of COVID-19 confirmed on 4 Feb 2020, Hong Kong has already experienced 4 waves of COVID-19 surge, with more than 9000 cases reported. A number of vaccines have been shown to be efficacious against symptomatic and severe infection by inducing neutralizing antibody (NAB) against spike protein of the SARS-CoV-2 virus. However, the duration of protection and longevity of antibody response is unknown.

Health care workers (HCWs) who are planning to receive COVID-19 vaccine will be recruited. The level of antibody against spike protein by different quantitative assays will also be serially measured .

Conditions

  • Covid-19 Vaccine

Interventions

BIOLOGICAL

CoronaVac Vaccine

CoronaVac Vaccine

BIOLOGICAL

BNT162b2 Vaccine

Covid-19 BNT162b2 Vaccine

Sponsors & Collaborators

  • Hong Kong Sanatorium & Hospital

    lead INDUSTRY

Principal Investigators

  • Jonpaul Sze Tsing Zee, MBChB · Hong Kong Sanatorium & Hotel

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-07
Primary Completion
2021-12-31
Completion
2021-12-31

Countries

  • Hong Kong

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04898946 on ClinicalTrials.gov