Trial Outcomes & Findings for Standardized Patients to Measure and Address Intersectional Stigma (NCT NCT04896216)

NCT ID: NCT04896216

Last Updated: 2024-07-31

Results Overview

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in MSM stigma within each arm (i.e. differences in care quality between men who have sex with men \[MSM\] vs. straight men). This outcome measures care quality related to whether or not doctors offered a syphilis test.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

59 participants

Primary outcome timeframe

4 months post-intervention

Results posted on

2024-07-31

Participant Flow

The study consisted of a baseline study visit, after which treatment arm providers received the training intervention. After the intervention, a follow-up visit was conducted for evaluation purposes. Randomization procedures were conducted at baseline.

Unit of analysis: clinics

Participant milestones

Participant milestones
Measure
Stigma Reduction Intervention
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
Standard of care (i.e. no training intervention)
Overall Study
STARTED
30 9
29 8
Overall Study
COMPLETED
27 9
18 7
Overall Study
NOT COMPLETED
3 0
11 1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Standardized Patients to Measure and Address Intersectional Stigma

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
Total
n=55 Participants
Total of all reporting groups
Age, Continuous
40 years
STANDARD_DEVIATION 9 • n=99 Participants
43 years
STANDARD_DEVIATION 9 • n=107 Participants
42 years
STANDARD_DEVIATION 9 • n=206 Participants
Sex: Female, Male
Female
11 Participants
n=99 Participants
10 Participants
n=107 Participants
21 Participants
n=206 Participants
Sex: Female, Male
Male
19 Participants
n=99 Participants
15 Participants
n=107 Participants
34 Participants
n=206 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Asian
30 Participants
n=99 Participants
25 Participants
n=107 Participants
55 Participants
n=206 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
White
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants

PRIMARY outcome

Timeframe: 4 months post-intervention

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in MSM stigma within each arm (i.e. differences in care quality between men who have sex with men \[MSM\] vs. straight men). This outcome measures care quality related to whether or not doctors offered a syphilis test.

Outcome measures

Outcome measures
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
MSM Stigma; Domain of Care: Syphilis Testing
0.078 percentage points
Interval -0.079 to 0.235
0.034 percentage points
Interval -0.181 to 0.248

PRIMARY outcome

Timeframe: 4 months post-intervention

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in HIV stigma within each arm (i.e. differences in care quality between HIV positive vs. HIV negative people). This outcome measures care quality related to whether or not doctors offered a syphilis test.

Outcome measures

Outcome measures
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
HIV Stigma; Domain of Care: Syphilis Testing
-0.201 percentage points
Interval -0.406 to 0.005
0.034 percentage points
Interval -0.181 to 0.248

PRIMARY outcome

Timeframe: 4 months post-intervention

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in intersectional stigma within each arm (i.e. differences in care quality between HIV positive MSM vs. HIV negative straight men). This outcome measures care quality related to whether or not doctors offered a syphilis test.

Outcome measures

Outcome measures
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
Intersectional Stigma; Domain of Care: Syphilis Testing
-0.07 percentage points
Interval -0.38 to 0.25
0 percentage points
Interval 0.0 to 0.0

PRIMARY outcome

Timeframe: 4 months post-intervention

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in MSM stigma within each arm (i.e. differences in care quality between men who have sex with men \[MSM\] vs. straight men). This outcome measures care quality related to the level of diagnostic effort expended by the doctor.

Outcome measures

Outcome measures
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
MSM Stigma; Domain of Care: Diagnostic Effort
-0.055 percentage points
Interval -0.862 to 0.752
0.396 percentage points
Interval -0.278 to 1.069

PRIMARY outcome

Timeframe: 4 months post-intervention

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in HIV stigma within each arm (i.e. differences in care quality between HIV positive vs. HIV negative people). This outcome measures care quality related to the level of diagnostic effort expended by the doctor.

Outcome measures

Outcome measures
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
HIV Stigma; Domain of Care: Diagnostic Effort
-0.570 percentage points
Interval -1.23 to 0.09
0.396 percentage points
Interval -0.278 to 1.069

PRIMARY outcome

Timeframe: 4 months post-intervention

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in intersectional stigma within each arm (i.e. differences in care quality between HIV positive MSM vs. HIV negative straight men). This outcome measures care quality related to the level of diagnostic effort expended by the doctor.

Outcome measures

Outcome measures
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
Intersectional Stigma; Domain of Care: Diagnostic Effort
0.621 percentage points
Interval -0.237 to 1.478
0.396 percentage points
Interval -0.278 to 1.069

PRIMARY outcome

Timeframe: 4 months post-intervention

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in MSM stigma within each arm (i.e. differences in care quality between men who have sex with men \[MSM\] vs. straight men). This outcome measures care quality related to the patient-centeredness of care provided.

Outcome measures

Outcome measures
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
MSM Stigma; Domain of Care: Patient-centered Care
-0.168 percentage points
Interval -0.595 to 0.259
-0.162 percentage points
Interval -0.852 to 0.528

PRIMARY outcome

Timeframe: 4 months post-intervention

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in HIV stigma within each arm (i.e. differences in care quality between HIV positive vs. HIV negative people). This outcome measures care quality related to the patient-centeredness of care provided.

Outcome measures

Outcome measures
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
HIV Stigma; Domain of Care: Patient-centered Care
0.408 percentage points
Interval -0.31 to 1.126
-0.162 percentage points
Interval -0.852 to 0.528

PRIMARY outcome

Timeframe: 4 months post-intervention

The outcome represents the amount by which stigma was reduced in each arm between baseline and follow-up. Positive values mean stigma indicate a decrease in stigma between the two time points. Negative values mean an increase in stigma between the two time points. Stigma itself was measured as the difference in healthcare quality between a stigmatized group vs. a dominant group. Because healthcare is multidimensional, we examined it across three domains: syphilis testing, diagnostic effort, and patient-centeredness of care. This outcome quantifies pre-post changes in intersectional stigma within each arm (i.e. differences in care quality between HIV positive MSM vs. HIV negative straight men). This outcome measures care quality related to the patient-centeredness of care provided.

Outcome measures

Outcome measures
Measure
Stigma Reduction Intervention
n=30 Participants
Experimental: a stigma reducation training intervention for providers employed at clinics randomized to the intervention arm. No intervention: standard of care (i.e. no training intervention)
Control
n=25 Participants
Standard of care (i.e. no training intervention)
Intersectional Stigma; Domain of Care: Patient-centered Care
-0.165 percentage points
Interval -0.836 to 0.506
-0.162 percentage points
Interval -0.852 to 0.528

Adverse Events

Stigma Reduction Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kumi Smith

University of Minnesota

Phone: 612.301.3051

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place