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Spontaneous Healing of ARticular Cartilage (SHARC)

NCT04889443 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2024-03-13

No results posted yet for this study

Summary

SHARC is an observational study of cartilage patients who are treated with surgery that involves obtaining a harvest biopsy. SHARC will study the natural healing process of the harvest biopsy site based on histological and biochemical analyses of repair tissue biopsies, synovial fluid biomarkers, medical imaging (MRI) and gait analysis.

Conditions

  • Cartilage Damage
  • Cartilage Injury

Interventions

PROCEDURE

Surgical cartilage repair procedure requiring harvest procedure or Autologous Stromal Cell Implantation

Any surgical cartilage repair procedure of the knee that requires a harvest biopsy of knee cartilage, which will leave a controlled small cartilage injury

Sponsors & Collaborators

  • Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust

    collaborator OTHER_GOV

  • Keele University

    lead OTHER

Principal Investigators

  • Jan Herman Kuiper, PhD · Keele University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04889443 on ClinicalTrials.gov