Phacotrabeculectomy Versus Phacogoniotomy (PVP) in Advanced Primary Angle-closure Glaucoma

Summary

A multicenter, parallel, open, non-inferior randomized controlled trial was conducted to compare the effectiveness and safety of phacotrabeculectomy and phacogoniotomy in the treatment of advanced primary angle closure glaucoma, so as to provide a better surgical alternative.

Conditions

• Glaucoma, Angle-Closure

Interventions

PROCEDURE

phacoemulsification with intraocular lens implantation combined with goniosynechialysis and goniotomy

The patients enrolled underwent phacoemulsification with intraocular lens implantation combined with goniosynechialysis and goniotomy.

PROCEDURE

phacoemulsification with intraocular lens implantation combined with trabeculectomy

The patients enrolled underwent phacoemulsification with intraocular lens implantation combined with trabeculectomy.

Sponsors & Collaborators

• The Second Affiliated Hospital of Harbin Medical University

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• First Hospital of Shijiazhuang City

  collaborator OTHER

• Union hospital of Fujian Medical University

  collaborator OTHER

• Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

  collaborator OTHER

• Handan City Eye Hospital

  collaborator UNKNOWN

• Chongqing Medical University

  collaborator OTHER

• Sun Yat-sen University

  lead OTHER

Principal Investigators

• Xiulan Zhang, MD, PhD · Zhongshan Ophthalmic Center, Sun Yat-sen University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

40 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-05-31

Primary Completion

2023-05-30

Completion

2025-06-30

Countries

• China

Study Locations