MedTrace Logo

Modulating the Locus Coeruleus Function

NCT04877782 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2023-10-23

No results posted yet for this study

Summary

The purpose of this study is to investigate the impact of transcutaneous vagus nerve stimulation (tVNS) on specific brain regions involved in memory and attention processes.

tVNS is a non-invasive and non-pharmacological technique known for targeting the locus coeruleus, a small subcortical nucleus in the brain thought to be involved in the earliest stages of Alzheimer's disease. This nucleus also plays a role in numerous cognitive functions, comprising memory and attention.

Conditions

  • Healthy Aging

Interventions

DEVICE

Transcutaneous vagus verne stimulation

Non-invasive and short electrical stimulation by placing the stimulating electrode at the cymba conchae of the left ear. The reference electrode is placed near the left cymba conchae. It provides a light tingling, massaging feeling in the ear.

Sponsors & Collaborators

  • University of Liege

    collaborator OTHER

  • Maastricht University Medical Center

    lead OTHER

Principal Investigators

  • Heidi IL Jacobs, Dr. · Maastricht University

Eligibility

Min Age
60 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-14
Primary Completion
2023-09-25
Completion
2023-10-05

Countries

  • Netherlands

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04877782 on ClinicalTrials.gov