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Breast Reconstruction in Previously Irradiated Breast

NCT04854525 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2150

Last updated 2021-04-22

No results posted yet for this study

Summary

For patients with breast cancer subject to a mastectomy, preserving the morphology of the breast with immediate reconstruction is a crucial aspect to preserve the quality of life.

There are several types of breast reconstruction: prosthetic in one or two stages and autologous reconstruction.

Adjuvant radiotherapy has shown an improvement of the overall survival and of the local control for patients with positive lymph nodes. As a consequence, plastic surgeons come into contact with more patients with a history of irradiation of their breasts than ever before.

However, there are few studies with a significant number that evaluate the effect of pre-reconstruction radiotherapy on the three types of reconstruction.

The aim of this study is to compare retrospectively these three types of reconstruction techniques to evaluate the impact of breast prior irradiation on the outcome of prosthetic reconstruction.

Conditions

  • Mammaplasty
  • Radiotherapy; Complications
  • Breast Implant; Complications
  • Transplant Failure

Interventions

RADIATION

Pre reconstruction Radiotherapy

Previous PMRT

Sponsors & Collaborators

  • Marco Klinger

    collaborator UNKNOWN

  • Marta Scorsetti

    collaborator UNKNOWN

  • Davide Franceschini

    collaborator UNKNOWN

  • Emanuela Morenghi

    collaborator UNKNOWN

  • Humanitas Clinical and Research Center

    lead OTHER

Principal Investigators

  • Marco Klinger · Humanitas Hospital, Italy

  • Davide Franceschini · Humanitas Hospital, Italy

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-06
Primary Completion
2020-11-23
Completion
2021-01-25

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04854525 on ClinicalTrials.gov