Endometrium Microbiome Alterations in Cesarean Section Diverticula Before and After Transvaginal Repair Surgery
NCT04847154 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2021-04-19
Summary
The study compares the microbiome differences in the endometrium between normal people and patients with uterine diverticula after cesarean section and aims to discover the essential microbes and their metabolites that highly associate with the repair of myometrium through metagenomics and metabolomics. It verifies that flora disorder in the endometrium is the important cause of poor uterine repair after cesarean section. Then these patients with uterine diverticula receive the transvaginal repair surgery. Through the follow-up with them, we gain the microbiome differences of the endometrium before and after the surgery and show the validity of transvaginal repair surgery in the level of microbiome and metabolism.
Conditions
- Cesarean Section Complications
Sponsors & Collaborators
-
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 35 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-04-12
- Primary Completion
- 2021-04-12
- Completion
- 2022-12-31
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