MedTrace Logo

Metabolic Syndrome and Degenerate Meniscus Tears

NCT04837456 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 189

Last updated 2021-04-08

No results posted yet for this study

Summary

The aim is to determine the outcomes of calorie-restricted diet and exercise intervention; libitum diet and waiting list control; early arthroscopic partial meniscectomy(APM) or delayed APM effect on MetS patients with Degenerate menisucus lesions.

Conditions

  • Metabolic Syndrome
  • Meniscus; Degeneration

Interventions

DIETARY_SUPPLEMENT

Calorie restricted diet and exercise intervention

the calorie restricted diet were prescribed a balanced diet that provided an energy deficit of 800 kcal/day from their daily energy requirement.Macronutrient content of low caloric diet, expressed as percentage of ingested energy with carbohydrates 45-65%; fat 20-35%; and protein 10- 35%\[36\]. Participants were guided by a dietitian for adjustments of their caloric intake weekly for six months.Participants performed 1 or 2 sets at a resistance of approximately 65% of their one-repetition maximum, with 8 to 12 repetitions of each exercise; they gradually increased the intensity to 2 to 3 sets at a resistance of approximately 80% of their one-repetition maximum, with 6 to 8 repetitions of each exercise.

PROCEDURE

libitum diet and waiting list control group

libitum diet and waiting list control group, participants then underwent a calorie of 2000 calorie above based on libitum free diets recommended to adults and normal physical activity without exercise during the program.

PROCEDURE

Early arthroscopic partial menisectomy group

Early APM group participants received APM with syndrome within 3 to 6 months

PROCEDURE

delayed APM group recruit participants with symptoms lasting for more than 6 months

delayed APM group recruit participants with symptoms lasting for more than 6 months

Sponsors & Collaborators

  • The First People's Hospital of Jingzhou

    lead OTHER

Principal Investigators

  • Hongyu Wang, Doctor · The First People's Hospital of Jingzhou

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-06-01
Primary Completion
2020-03-01
Completion
2021-03-01

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04837456 on ClinicalTrials.gov