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Respiratory Muscle Endurance in Obesity Hypoventilation Syndrome

NCT04835558 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2021-04-08

No results posted yet for this study

Summary

Obesity hypoventilation syndrome (OHS) is defined as a combination of obesity \[body mass index (BMI) ≥30 kg/m2\], chronic daytime hypercapnia (PaCO2 \>45 mm Hg), and sleep-apnea in the absence of other known causes of hypercapnia. Respiratory system compliance decreases and resistance increases in OHS. This causes increase in work of breathing and oxygen cost of breathing, which may result in respiratory muscle fatigue. Increase in respiratory workload and increase in resistance to respiration is expected to decrease in respiratory muscle endurance (RME) in subjects with OHS.

Conditions

  • Obesity Hypoventilation Syndrome (OHS)

Sponsors & Collaborators

  • Istanbul University

    lead OTHER

Eligibility

Min Age
24 Years
Max Age
69 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-05
Primary Completion
2018-11-05
Completion
2019-01-24

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04835558 on ClinicalTrials.gov