Regorafenib Treatment Patterns and Survival Outcomes in Advanced Colorectal Cancer: A Real-world Study

Summary

This is a multi-center, retrospective, real-world study. The purpose of this study is to observe the effectiveness and safety of regorafenib in Chinese advanced colorectal cancer patients.

The main observational goals include overall survival(OS), 6 month OS rate, 1 year OS rate, and treatment time failure (TTF), other study goals include objective response rate( ORR)、Disease control rate（DCR）and adverse event(AE) of regorafenib.

Conditions

• Advanced Colorectal Cancer

Sponsors & Collaborators

• Beijing Hospital

  collaborator OTHER_GOV

• Jiangsu Cancer Institute & Hospital

  collaborator OTHER

• The Affiliated Hospital of Qingdao University

  collaborator OTHER

• Shanxi Province Cancer Hospital

  collaborator OTHER

• Affiliated Hospital of Hebei University

  collaborator OTHER

• Shandong Cancer Hospital and Institute

  collaborator OTHER

• The First Affiliated Hospital of Zhengzhou University

  collaborator OTHER

• Hebei Medical University Fourth Hospital

  collaborator OTHER

• First Hospital of China Medical University

  collaborator OTHER

• Chinese Academy of Medical Sciences

  lead OTHER

Principal Investigators

• Yunbo Zhao · Beijing Hospital

• Liangjun Zhu · Jiangsu Cancer Institute & Hospital

• Zimin Liu · The Affiliated Hospital of Qingdao University

• Wei Bai · Shaanxi Provincial Cancer Hospital

• Aimin Zang · Affiliated Hospital of Hebei University

• Bo Liu · Shandong Cancer Hospital and Institute

• Hong Zong · The First Affiliated Hospital of Zhengzhou University

• Shengmian Li · The fourth hospital of Hebei medical university and hebei cancer hospital

• Xiujuan Qu · First Hospital of China Medical University

• Aiping Zhou · Cancer Hospital Chinese Academy of Medical Science

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2020-10-01

Primary Completion

2022-02-01

Completion

2022-10-01

Countries

• China

Study Locations