Compare Effects of Dressing With Honey and EUSOL
NCT04831112 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 326
Last updated 2022-11-15
Summary
Honey is super saturated solution containing sugar derived from nectar gathered by honeybee. Honey is viscus supersaturated solution mainly composed of sugar and water along with minor constituents such as minerals, vitamins, amino acids, organic acids, flavonoids, and other phenolic compound and aromatic substances. Honey contents according to percentages are fructose 38.6%, glucose 31%, water 17%, lactose 7.2%, larger sugars 4.7% and rest of micronutrients and elemental compounds are 1.5%. Honey enhances wound healing by removing slough and necrotic tissue from wound. It promotes wound healing by increasing angiogenesis, granulation and epithelization. Honey possess antimicrobial activity against bacteria like methicillin resistant staphylococcus aureus, vancomycin resistant Escherichia Coli, pseudomonas aeruginosa, and many other species. It also has activity against some yeast species such as aspergillus and penicillium.
Honey used for dressing will be 'Langnese Honey". Langnese honey is raw honey / unprocessed packed as collected, quality and quantity will be same for patients.
Conditions
- Necrotizing Fascitis
- Wound Infection
Interventions
- DRUG
-
Honey
Dressing of necrotizing fascitis wounds with honey.
- COMBINATION_PRODUCT
-
EUSOL
Dressing of necrotizing fascitis wounds with EUSOL.
Sponsors & Collaborators
-
Dow University of Health Sciences
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-03-01
- Primary Completion
- 2021-12-31
- Completion
- 2021-12-31
Countries
- Pakistan
Study Locations
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