Trial Outcomes & Findings for Effects of Smoking State on Decision Making (NCT NCT04826276)
NCT ID: NCT04826276
Last Updated: 2026-05-01
Results Overview
number of high effort selections
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
5 participants
Primary outcome timeframe
approximately 2 weeks
Results posted on
2026-05-01
Participant Flow
Participant milestones
| Measure |
Satiated/Withdrawn
first satiated then withdrawn
|
Withdrawn/Satiated
first tobacco/nicotine withdrawn then tobacco/nicotine satiated
|
|---|---|---|
|
Overall Study
STARTED
|
3
|
2
|
|
Overall Study
COMPLETED
|
3
|
2
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Effects of Smoking State on Decision Making
Baseline characteristics by cohort
| Measure |
Satiated/Withdrawn
n=3 Participants
first satiated then withdrawn
|
Withdrawn/Satiated
n=2 Participants
first withdrawn then satiated
|
Total
n=5 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Race (NIH/OMB)
Asian
|
0 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
0 Participants
n=69 Participants
|
|
Age, Categorical
<=18 years
|
0 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
0 Participants
n=69 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
3 Participants
n=14 Participants
|
2 Participants
n=34 Participants
|
5 Participants
n=69 Participants
|
|
Age, Categorical
>=65 years
|
0 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
0 Participants
n=69 Participants
|
|
Age, Continuous
|
34.6 years
STANDARD_DEVIATION 11.44 • n=14 Participants
|
26.5 years
STANDARD_DEVIATION 5.5 • n=34 Participants
|
31.4 years
STANDARD_DEVIATION 10.3 • n=69 Participants
|
|
Sex: Female, Male
Female
|
0 Participants
n=14 Participants
|
1 Participants
n=34 Participants
|
1 Participants
n=69 Participants
|
|
Sex: Female, Male
Male
|
3 Participants
n=14 Participants
|
1 Participants
n=34 Participants
|
4 Participants
n=69 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
0 Participants
n=69 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
0 Participants
n=69 Participants
|
|
Race (NIH/OMB)
Black or African American
|
2 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
2 Participants
n=69 Participants
|
|
Race (NIH/OMB)
White
|
1 Participants
n=14 Participants
|
2 Participants
n=34 Participants
|
3 Participants
n=69 Participants
|
|
Race (NIH/OMB)
More than one race
|
0 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
0 Participants
n=69 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
0 Participants
n=69 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
0 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
0 Participants
n=69 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
3 Participants
n=14 Participants
|
2 Participants
n=34 Participants
|
5 Participants
n=69 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=14 Participants
|
0 Participants
n=34 Participants
|
0 Participants
n=69 Participants
|
|
Region of Enrollment
United States
|
3 participants
n=14 Participants
|
2 participants
n=34 Participants
|
5 participants
n=69 Participants
|
|
cigarettes per day
|
4.2 cigarettes per day
STANDARD_DEVIATION 4.2 • n=14 Participants
|
10 cigarettes per day
STANDARD_DEVIATION 0 • n=34 Participants
|
7.6 cigarettes per day
STANDARD_DEVIATION 3.8 • n=69 Participants
|
PRIMARY outcome
Timeframe: approximately 2 weeksnumber of high effort selections
Outcome measures
| Measure |
Withdrawn Then Satiated
n=2 Participants
withdrawn then satiated
|
Satiated Then Withdrawn
n=3 Participants
satiated then withdrawn
|
|---|---|---|
|
Effort Based Decision Making
|
29.5 high effort selections
Standard Deviation 16.5
|
18.3 high effort selections
Standard Deviation 2.62
|
PRIMARY outcome
Timeframe: approximately 2 weeksduration on measures of distress tolerance
Outcome measures
| Measure |
Withdrawn Then Satiated
n=2 Participants
withdrawn then satiated
|
Satiated Then Withdrawn
n=3 Participants
satiated then withdrawn
|
|---|---|---|
|
Distress Tolerance Behavior
|
615883 secs
Standard Deviation 584133
|
24448 secs
Standard Deviation 26634
|
Adverse Events
Withdrawn Then Satiated
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Satiated Then Withdrawn
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Dr. Merideth Addicott
Wake Forest University School of Medicine
Phone: 336-716-7792
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place