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Blood Transfusion Reduction - QI Project

NCT04823273 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1640

Last updated 2023-05-10

No results posted yet for this study

Summary

Blood Banks of large medical centers have large annual budgets, typically millions of dollars. Blood product wastage results in not only in a loss of the product's cost, but also of the fees involved in transporting, handling, and administering these products. Optimal utilization of blood products requires a balance between maximizing patient clinical outcomes while avoiding unnecessary costs and risks associated with transfusions. This project will specifically focus on packed red blood cell transfusions (pRBCs). There are clear guidelines for transfusing pRBCs however these guidelines are not always followed. pRBC transfusions outside of recommended guidelines is associated with increased risk of harm to patients.

Our aim is to improve adherence to guideline indicated pRBC transfusions for patient in the UCHealth system thereby decreasing inappropriate (non-guideline indicated) pRBC transfusions. We will conduct a QI project seeking to improve pRBC transfusion guideline adherence. This project will involve data review to establish baseline rates, multimodal interventions to improve adherence to pRBC transfusion guidelines including provider education, modifications to the electronic ordering interface, and changing blood back policies at participating institutions.

Conditions

  • Blood Transfusion

Interventions

BEHAVIORAL

General improvement

Changes to interface to be more intuitive.

BEHAVIORAL

In-line help text

General improvement + in-line help text

BEHAVIORAL

Interruptive alert

General improvement + interruptive alert

Sponsors & Collaborators

  • University of Colorado, Denver

    lead OTHER

Principal Investigators

  • Michael Ho, MD, PhD · University of Colorado Denver Anschutz Medical Campus

  • Tyler Anstett, DO · University of Colorado Denver Anschutz Medical Campus

Study Design

Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-04-06
Primary Completion
2022-04-05
Completion
2022-10-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04823273 on ClinicalTrials.gov