Study of AMG 160 in Subjects With Non-Small Cell Lung Cancer
NCT04822298 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 3
Last updated 2024-07-05
Summary
This study aims to evaluate the safety and tolerability of AMG 160 and to evaluate the maximum tolerated dose (MTD) or the recommended phase 2 dose (RP2D).
Conditions
Interventions
- DRUG
-
AMG 160
AMG 160 administered as an intravenous (IV) infusion
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
MD · Amgen
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-08-31
- Primary Completion
- 2021-12-08
- Completion
- 2022-01-26
- FDA Drug
- Yes
Countries
- United States
- Australia
- Austria
Study Locations
More Related Trials
-
Phase 1b/2 Trial of AMG386 With Pemetrexed and Carboplatin in Non-Small Cell Lung Cancer
NCT01666977 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase 2 Study of Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer
NCT02117024 ·Status: TERMINATED ·Phase: PHASE2
-
Camrelizumab With Apatinib as Neoadjuvant Therapy for Participants With Resectable Non-Small Cell Lung Cancer
NCT04506242 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Phase 1b/2 Study of AMG 655 in Combination With Paclitaxel and Carboplatin for the First-Line Treatment of Advanced Non-Small Cell Lung Cancer
NCT00534027 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Camrelizumab Combined With Albumin-bound Paclitaxel and Platinum in Neoadjuvant Treatment of Resectable NSCLC
NCT04338620 ·Status: UNKNOWN ·Phase: PHASE2
-
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
NCT05624996 ·Status: RECRUITING ·Phase: PHASE3
-
A Phase II Trial of Camrelizumab Combined With Famitinib for Adjuvant Treatment of Stage II-IIIA NSCLC.
NCT05005468 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study to Evaluate SHR-1210 in Combination With Famitinib Plus Chemotherapy in Subjects With NSCLC.
NCT04619433 ·Status: TERMINATED ·Phase: PHASE3
-
Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
NCT04625647 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Motesanib (AMG 706) in Combination With Paclitaxel and Carboplatin for Advanced Non-Squamous Non-Small Cell Lung Cancer
NCT02629848 ·Status: TERMINATED ·Phase: PHASE3
-
Neoadjuvant PD-1 Antibody Plus Chemotherapy in Resectable Stage IIIA-N2 Non-Small-Cell Lung Cancer
NCT04422392 ·Status: TERMINATED ·Phase: PHASE2
-
Camrelizumab Combined With Apatinib, Etoposide and Cisplatin Treat Small-cell Lung Cancer.
NCT04490421 ·Status: UNKNOWN ·Phase: PHASE3
-
A Phase 2 Trial of AMG 706 or Bevacizumab in Combination With Chemo for Advanced NSCLC
NCT00369070 ·Status: TERMINATED ·Phase: PHASE2
-
Study to Compare AMG 510 "Proposed INN Sotorasib" With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBreak 200).
NCT04303780 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Neoadjuvant Chemo for Non-metastatic Non-small Cell Lung Cancer
NCT01860040 ·Status: TERMINATED ·Phase: PHASE2
-
RO4929097 in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Recently Completed Treatment With Front-Line Chemotherapy
NCT01193868 ·Status: TERMINATED ·Phase: PHASE2
-
S0022:Combination Chemotherapy and Radiation Therapy in Treating Patients With Stage IIIB Non-Small Cell Lung Cancer
NCT00014196 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Camrelizumab Combined With Chemotherapy Sequential Camrelizumab Combined With Apatinib Treatment of Advanced NSCLC
NCT04950400 ·Status: UNKNOWN ·Phase: NA
-
Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer: AIM-HIGH (Adjuvant Intervention in Molecular High Risk Patients)
NCT01817192 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Study of Durvalumab + Tremelimumab in NSCLC Patients After Adjuvant Treatment
NCT04625699 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study of AMG 951 [rhApo2L/TRAIL] in Subjects With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) Treated With Chemotherapy +/- Bevacizumab
NCT00508625 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 2 Study of MPDL3280A Combined With CDX-1401 in NY-ESO 1 (+) IIIB, IV or Recurrent Non-Small Cell Lung Cancer
NCT02495636 ·Status: WITHDRAWN ·Phase: PHASE2
-
Immunodynamics-Guided Optimization of Individualized Immunochemotherapy in Advanced Driver-Negative NSCLC: A Randomized Trial
NCT07190027 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Adjuvant Chemotherapy Combined With Camrelizumab for ⅡA -ⅢA NSCLC Patients
NCT05825443 ·Status: RECRUITING ·Phase: PHASE2
-
Vaccine Maintenance Treatment for Non-Small Cell Lung Cancer
NCT00420732 ·Status: TERMINATED ·Phase: PHASE2