Load-induced Changes in Glenohumeral Translation in Patients With Rotator Cuff Tear

Summary

The study is to investigate the dose-response relationship between load-induced muscle activation (liMA) and load-induced glenohumeral translation (liTr) in patients with rotator cuff tears and asymptomatic control subjects.

Furthermore the study is to investigate the in vivo dose-response relationship between additional weight and glenohumeral translation, to understand the biological variation in liTr, the influence of disease pathology on the liTr, the potential compensation by muscle activation and muscle size, and the influence of liTr on patient outcomes.

Conditions

• Rotator Cuff Tear

Interventions

DIAGNOSTIC_TEST

3D motion analysis

30° arm abduction in the scapular plane will be performed with and without a handheld weight of 1, 2, 3, and 4 kg. All movements will be done bilaterally. Electromyographic (EMG) data of arm and trunk muscles will be recorded using surface electrodes. Participants will be asked to perform full arm abduction with different rotations (internal, neutral and external rotation), flexion and internal-/external rotations movements (without additional handheld weight).

DIAGNOSTIC_TEST

isometric shoulder strength by dynamometer

isometric shoulder strength for abduction and internal/external rotation will be assessed with a isometric shoulder strength for abduction and internal/external rotation will be assessed with a dynamometer

DIAGNOSTIC_TEST

fluoroscopic images of each shoulder

fluoroscopic images (Multitom Rax, Siemens Healthineers, Erlangen, Germany) of each shoulder will be taken during the 30° arm abduction test with and without a handheld weight (0, 2, and 4kg)

DIAGNOSTIC_TEST

Bilateral shoulder Magnetic Resonance Imaging (MRI)

MRI of both shoulders will be taken

OTHER

data collection by health questionnaires

data collection by health questionnaires

Sponsors & Collaborators

• Swiss National Science Foundation

  collaborator OTHER

• University Hospital, Basel, Switzerland

  lead OTHER

Principal Investigators

• Annegret Mündermann, Prof. Dr. · Department of Orthopaedics and Traumatology, University Hospital Basel

Study Design

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

20 Years

Max Age

85 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2021-05-04

Primary Completion

2022-12-31

Completion

2023-12-31

Countries

• Switzerland

Study Locations