Application of KANG FU PEN in Radical Concurrent Radiotherapy and Chemotherapy for Cervical Cancer to Prevent and Treat Radiation-induced Rectal Injury

Summary

A total of 520 cases will be randomly divided into Kang Fu Pen (liquid dressing) enema intervention group (experimental group) and non-enema intervention group (control group), according to the ratio of 1:1.

Conditions

• Cervical Cancer
• Radiotherapy Side Effect
• Radiotherapy; Complications

Interventions

DRUG

KANG FU PEN

FU PEN: anti-radiation spray (liquid dressing) treatment which is a protective irrigation solution against rays

Sponsors & Collaborators

• Cancer Institute and Hospital, Chinese Academy of Medical Sciences

  collaborator OTHER

• Chinese PLA General Hospital

  collaborator OTHER

• Peking University Third Hospital

  collaborator OTHER

• Peking University Cancer Hospital & Institute

  collaborator OTHER

• Jiangsu Cancer Institute & Hospital

  collaborator OTHER

• Sichuan Cancer Hospital and Research Institute

  collaborator OTHER

• Sun Yat-sen University

  collaborator OTHER

• Jilin Provincial Tumor Hospital

  collaborator OTHER

• Fudan University

  collaborator OTHER

• Shandong Cancer Hospital and Institute

  collaborator OTHER

• The First Affiliated Hospital of Air Force Medicial University

  collaborator OTHER

• Guizhou Cancer Hospital (The Affiliated Cancer Hospital of Guizhou Medical University)

  collaborator UNKNOWN

• Zhejiang Cancer Hospital

  collaborator OTHER

• Xiangya Hospital of Central South University

  collaborator OTHER

• Henan Cancer Hospital

  collaborator OTHER_GOV

• Peking Union Medical College Hospital

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

FEMALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-03-01

Primary Completion

2023-03-01

Completion

2025-03-01

Countries

• China

Study Locations