Trial Outcomes & Findings for Validation of a Novel Non-invasive Continuous Blood Pressure Monitor in Children Ages 2- 17 Years-old (NCT NCT04817137)

NCT ID: NCT04817137

Last Updated: 2026-07-23

Results Overview

The accuracy of blood pressure measurements (systolic) taken from the non-invasive blood pressure device will be compared to measurements taken from the patient's indwelling arterial line, which will be place as part of standard of care.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

35 participants

Primary outcome timeframe

One hour during procedure

Results posted on

2026-07-23

Participant Flow

Participant milestones

Participant milestones
Measure
All Enrolled Patients
Patients will wear the Caretaker Pulse Decomposition Analysis (PDA) Device, which will record the patient's blood pressure. CareTaker PDA Device: Non-invasive blood pressure monitoring
Overall Study
STARTED
35
Overall Study
COMPLETED
31
Overall Study
NOT COMPLETED
4

Reasons for withdrawal

Reasons for withdrawal
Measure
All Enrolled Patients
Patients will wear the Caretaker Pulse Decomposition Analysis (PDA) Device, which will record the patient's blood pressure. CareTaker PDA Device: Non-invasive blood pressure monitoring
Overall Study
Case Cancelled
1
Overall Study
Change in Clinical Plan
3

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
All Enrolled Patients
n=31 Participants
Patients will wear the Caretaker Pulse Decomposition Analysis (PDA) Device, which will record the patient's blood pressure.
Age, Categorical
<=18 years
31 Participants
n=31 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=31 Participants
Age, Categorical
>=65 years
0 Participants
n=31 Participants
Sex: Female, Male
Female
20 Participants
n=31 Participants
Sex: Female, Male
Male
11 Participants
n=31 Participants
Region of Enrollment
United States
31 Participants
n=31 Participants
Weight
32.7 kg
STANDARD_DEVIATION 18.7 • n=31 Participants

PRIMARY outcome

Timeframe: One hour during procedure

The accuracy of blood pressure measurements (systolic) taken from the non-invasive blood pressure device will be compared to measurements taken from the patient's indwelling arterial line, which will be place as part of standard of care.

Outcome measures

Outcome measures
Measure
All Enrolled Patients
n=31 Participants
Patients will wear the Caretaker Pulse Decomposition Analysis (PDA) Device, which will record the patient's blood pressure.
Blood Pressure Comparison (Systolic)
-3.79 mm Hg
Standard Deviation 9.74

PRIMARY outcome

Timeframe: One hour during procedure

The accuracy of blood pressure measurements (diastolic) taken from the non-invasive blood pressure device will be compared to measurements taken from the patient's indwelling arterial line, which will be place as part of standard of care.

Outcome measures

Outcome measures
Measure
All Enrolled Patients
n=31 Participants
Patients will wear the Caretaker Pulse Decomposition Analysis (PDA) Device, which will record the patient's blood pressure.
Blood Pressure Comparison (Diastolic)
1.72 mm Hg
Standard Deviation 8.445

PRIMARY outcome

Timeframe: One hour during procedure

The accuracy of blood pressure measurements (mean) taken from the non-invasive blood pressure device will be compared to measurements taken from the patient's indwelling arterial line, which will be place as part of standard of care.

Outcome measures

Outcome measures
Measure
All Enrolled Patients
n=31 Participants
Patients will wear the Caretaker Pulse Decomposition Analysis (PDA) Device, which will record the patient's blood pressure.
Blood Pressure Comparison (Mean)
2.41 mm Hg
Standard Deviation 8.57

Adverse Events

All Enrolled Patients

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Karen Boretsky

Boston Children's Hospital

Phone: 617-355-7243

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place