The Use of Expandeded Mesenchymal Stromal Cells (MSC) in Premature Ovarian Failure (POF) in Adult Humans
NCT04815213 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2025-01-28
Summary
Autologous bone marrow-derived mesenchymal cells will be injected into patients diagnosed with premature ovarian failure
Conditions
- Premature Ovarian Failure
Interventions
- BIOLOGICAL
-
expanded autologous bone marrow derived MSC Intravaginally
Autologous bone marrow-derived mesenchymal cells (BMMSCs), dose 20 million cells/ovary
- BIOLOGICAL
-
expanded autologous bone marrow derived MSC Laporoscopic
Autologous bone marrow-derived mesenchymal cells (BMMSCs), dose 20 million cells/ovary
- BIOLOGICAL
-
EV
Extracellular vesicles injection
Sponsors & Collaborators
-
University of Jordan
lead OTHER
Principal Investigators
-
Dr Abdalla Awidi, MD · Cell therapy center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 38 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-01-01
- Primary Completion
- 2025-01-31
- Completion
- 2027-01-31
Countries
- Jordan
Study Locations
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