Tenofovir-DF Versus Hydroxychloroquine in the Treatment of Hospitalized Patients With COVID-19 (TEDHICOV)
NCT04812496 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2021-03-25
Summary
Although several therapeutic agents have been suggested for the treatment of the disease caused by the Coronavirus of the year 2019 (COVID-19), no antiviral has yet demonstrated consistent efficacy.
This is an observational study comparing Tenofovir-DF (disoproxil fumarate) (TDF) with Hydroxychloroquine (HCQ) in the treatment of hospitalized patients with COVID-19 with evidence of pulmonary compromise and with supplemental oxygen required.
Conditions
- Covid19
- SARS-CoV Infection
- Tenofovir
Sponsors & Collaborators
-
Hospital Nacional Carlos Alberto Seguin Escobedo - EsSalud
lead OTHER
Principal Investigators
-
Mario Cornejo-Giraldo, M.D. · Head of the Infectious Diseases Unit
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-03-01
- Primary Completion
- 2020-05-30
- Completion
- 2021-01-15
Countries
- Peru
Study Locations
More Related Trials
-
An Efficacy and Safety Study of Telaprevir in Patients Infected With Both Chronic Hepatitis C Virus (HCV-1) and Human Immunodeficiency Virus (HIV-1)
NCT01513941 ·Status: COMPLETED ·Phase: PHASE3
-
To Evaluate Efficacy and Safety in TG-2349 Combination With DAG181 (± Ribavirin) in HCV Genotype I Infected Patients
NCT03593447 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Trial For Early SARS-CoV-2 (COVID-19) Treatment
NCT04981379 ·Status: COMPLETED ·Phase: PHASE3
-
Ropeginterferon Alfa-2b (P1101) Phase 3 Study in Interferon Treatment-Naive Subjects With HCV Genotype 2 Infection
NCT04382937 ·Status: COMPLETED ·Phase: PHASE3
-
TMC435-TiDP16-C114 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and the Antiretroviral Agents TMC278 and Tenofovir
NCT01205139 ·Status: COMPLETED ·Phase: PHASE1
-
Lopinavir/ Ritonavir, Ribavirin and IFN-beta Combination for nCoV Treatment
NCT04276688 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of RO5024048 in Combination With Ritonavir-Boosted Danoprevir With or Without Copegus (Ribavirin) in Interferon-Naïve Patients With Chronic Hepatitis C Genotype 1 (INFORM-SVR)
NCT01278134 ·Status: COMPLETED ·Phase: PHASE2
-
Different PEG-interferon and Ribavirin Schedules for Chronic Hepatitis C in the Real Clinical Practice.
NCT01195181 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Examine Multiple Doses of TMC647055 in Combination With Telaprevir
NCT01582035 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy, Safety and Tolerability of Ribavirin Monotherapy Followed by Combined Treatment With Ribavirin and Hydroxychloroquine in Patients Infected With Hepatitis C
NCT01833845 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Study of TMC435 in Participants With Genotype 1 Hepatitis C Virus (HCV) Infection
NCT01366638 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase III Study of TMC435 in Genotype 1, Hepatitis C-infected Participants Who Failed to Respond to Previous IFN-based Therapy
NCT01288209 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Trial to Assess Safety and Efficacy of Combination Therapy: Hydroxychloroquine, Pegylated Interferon Alpha-2a and Ribavirin in Chronic Hepatitis C Subjects Non-responders to the Standard of Care Therapy.
NCT01272310 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study of Mericitabine in Combination With Telaprevir and Peginterferon Alfa-2a / Ribavirin in Participants With Chronic Hepatitis C
NCT01482390 ·Status: COMPLETED ·Phase: PHASE2
-
Early Access Program of Telaprevir With Peginterferon and Ribavirin in Chronic Hepatitis C Subjects
NCT01508286 ·Status: NO_LONGER_AVAILABLE
-
Two Different Treatments 24 vs 48 Weeks Chronic Hepatitis C Genotypes 2 and/or 3 in co-Infected HIV-HCV
NCT00611819 ·Status: UNKNOWN ·Phase: PHASE4
-
A Phase 3 Study of Telaprevir in Combination With Pegasys® and Copegus® in Treatment-Naive Subjects With Genotype 1 Hepatitis C Virus (HCV)
NCT00627926 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Combination Treatment With an HCV Polymerase Inhibitor (RO5024048) and an HCV Protease Inhibitor (RO5190591/Danoprevir) in Genotype 1 Chronic Hepatitis C Patients
NCT00801255 ·Status: COMPLETED ·Phase: PHASE1
-
Open Label Study to Compare Efficacy, Safety and Tolerability of Hydroxychloroquine Combined With Azithromycin Compared to Hydroxychloroquine Combined With Camostat Mesylate and to "no Treatment" in SARS CoV 2 Virus
NCT04355052 ·Status: UNKNOWN ·Phase: PHASE3
-
Virology Follow up Study in Subjects Previously Treated With Telaprevir
NCT00916474 ·Status: COMPLETED
-
Safety and Efficacy of Telaprevir in Combination With Peginterferon Alfa-2a and Ribavirin in Subjects Co-Infected With Hepatitis C Virus (HCV) and HIV
NCT00983853 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Pegylated Interferon Plus Ribavirin Plus Nitazoxanide in HCV Genotype 4 and HIV Coinfection
NCT01529073 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase III Study to Evaluate Efficacy and Safety of TG-2349 in Combination With DAG181 and RBV for HCV Type I Patients
NCT04155515 ·Status: COMPLETED ·Phase: PHASE3
-
Study Comparing Daclatasvir (BMS-790052) With Telaprevir Combined With Peginterferon Alfa-2a and Ribavirin in Patients With Chronic Hepatitis C Virus Infection
NCT01492426 ·Status: COMPLETED ·Phase: PHASE3
-
An Observational Study of Peginterferon (e.g. Pegasys)-Based Direct Acting Antiviral Triple Therapy in Patients With Chronic Hepatitis C Genotype 1
NCT01508130 ·Status: COMPLETED