Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors
NCT04803318 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2024-06-25
Summary
To study the clinical effect of Trametinib combined with Everolimus and Lenvatinib in the treatment of Recurrent/Refractory advanced solid tumors.
Conditions
- Solid Tumor, Adult
- Hepatocellular Carcinoma
Interventions
- DRUG
-
Combination of three inhibitors Trametinib, Everolimus and Lenvatinib
Oral administration of three inhibitors including Trametinib, Everolimus and Lenvatinib.
Sponsors & Collaborators
-
Second Affiliated Hospital of Guangzhou Medical University
lead OTHER
Principal Investigators
-
Zhenfeng Zhang, MD, PhD · Second Affiliated Hospital of Guangzhou Medical University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-01-01
- Primary Completion
- 2029-01-01
- Completion
- 2037-01-01
- FDA Drug
- Yes
Countries
- China
Study Locations
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