a Study of SHR1210 in Combination With Paclitaxel-albumin and Carboplatin in Extensive Stage Small Cell Lung Cancer
NCT04790539 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 71
Last updated 2021-03-10
Summary
This project is to to explore the safety and efficacy of shr-1210 combined with albumin, paclitaxel and carboplatin in the first-line treatment of extensive small cell lung cancer
Conditions
Interventions
- DRUG
-
SHR-1210
SHR-1210 is a humanized anti-PD-1 IgG4 monoclonal antibody
Sponsors & Collaborators
-
Shanghai Pulmonary Hospital, Shanghai, China
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-04-01
- Primary Completion
- 2022-05-01
- Completion
- 2022-12-31
More Related Trials
-
A Study to Evaluate SHR-1210 in Combination With Famitinib Plus Chemotherapy in Subjects With NSCLC.
NCT04619433 ·Status: TERMINATED ·Phase: PHASE3
-
The Study is Being Conducted to Evaluate the Efficacy and Safety of SHR-1316 in Combination With Chemo-radiotherapy in Patients With LS-SCLC.
NCT04691063 ·Status: UNKNOWN ·Phase: PHASE3
-
Phase II Clinical Study of SHR2554 Tablets Combined With Other Anti-tumor Treatments in Non-small Cell Lung Cancer Subjects
NCT07175220 ·Status: RECRUITING ·Phase: PHASE2
-
SHR-A1921 Combined With Adebrelimab in the Treatment of Advanced NSCLC Who Failed the Previous Standard First-line Treatment
NCT06480136 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Combined Simvastatin and Albumin Paclitaxel in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy
NCT04698941 ·Status: UNKNOWN ·Phase: PHASE2
-
A Trial of SHR-1316/Placebo in Combination With Chemotherapy in Patients With Resectable NSCLC
NCT04316364 ·Status: RECRUITING ·Phase: PHASE3
-
A Study of SHR-1210 in Combination With Pemetrexed and Carboplatin in Subjects With Non-squamous NSCLC
NCT03134872 ·Status: COMPLETED ·Phase: PHASE3
-
SHR-1316 Combined With Chemotherapy and Chest Radiotherapy in ES-SCLC
NCT04562337 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Open-Label, Biomarker-Integrated Umbrella Trial for First-Line Treatment of Extensive-stage Small Cell Lung Cancer
NCT07172412 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Adebrelimab Combined With Bevacizumab and Albumin Paclitaxel in Non-squamous NSCLC After First-line Treatment
NCT05738317 ·Status: UNKNOWN ·Phase: PHASE2
-
Combined Atezolizumab and Chemotherapy (Carboplatin Plus Etoposide) in Neoadjuvant Treating Limited-Stage Small Cell Lung Cancer Patients
NCT04696939 ·Status: UNKNOWN ·Phase: PHASE2
-
CM082 and JS001 in Patients With Advanced Small-cell Lung Cancer (SCLC)
NCT03904719 ·Status: UNKNOWN ·Phase: PHASE2
-
SKB500 Combinations in Patients With Small Cell Lung Cancer
NCT07296809 ·Status: RECRUITING ·Phase: PHASE2
-
Nab-paclitaxel as Second-line Therapy in Locally Advanced or Metastatic Squamous Lung Cancer
NCT01969955 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Efficacy Study of Abraxane in Combination With Carboplatin to Treat Advanced NSCL Cancer in the Elderly
NCT02151149 ·Status: COMPLETED ·Phase: PHASE4
-
Adebrelimab + Apatinib in SCLC Maintenance Therapy
NCT06475209 ·Status: RECRUITING ·Phase: PHASE2
-
Camrelizumab With Apatinib as Neoadjuvant Therapy for Participants With Resectable Non-Small Cell Lung Cancer
NCT04506242 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Efficacy and Safety of IBI308 and Paclitaxel/Albumin Paclitaxel for SCLC Patients Who Failed Etoposide Chemotherapy
NCT04056949 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Plus Docetaxel as 2nd Line Treatment in Patients With Advanced Non-squamous and Non-small Cell Lung Cancer
NCT02780778 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
A Study of Nab-Paclitaxel and Carboplatin Plus Necitumumab (LY3012211) in Participants With Stage IV Squamous NSCLC
NCT02392507 ·Status: COMPLETED ·Phase: PHASE2
-
Adebrelimab Plus Chemotherapy as Neoadjuvant Therapy in Resectable NSCLC Harboring Driver Gene Mutations
NCT06299371 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Study of Low-Dose Radiotherapy Concurrent Chemotherapy With Serplulimab for Patients With ES-SCLC
NCT05765825 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy in Extensive-Stage Small Cell Lung Cancer
NCT05309629 ·Status: COMPLETED ·Phase: PHASE2
-
Durvalumab Combined With Chemotherapy and Stereotactic Body Radiotherapy (SBRT) in Patients With Oligometastatic Non-small Cell Lung Cancer (NSCLC)
NCT04255836 ·Status: UNKNOWN ·Phase: PHASE2
-
Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer
NCT04262856 ·Status: COMPLETED ·Phase: PHASE2