Trial Outcomes & Findings for Public Messaging to Increase Treatment Seeking for Veterans at Risk for Suicide (NCT NCT04784663)

NCT ID: NCT04784663

Last Updated: 2026-07-09

Results Overview

yes to initiating psychological treatment and/or medication/pharmacological treatment in the past month to treat mental health issues.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

355 participants

Primary outcome timeframe

baseline through 2-month follow-up

Results posted on

2026-07-09

Participant Flow

A national random sample was recruited for the trial from December 2022 through April 2025 using the VA and DoD administrative records of those who recently separated from active components of service branches plus activated National Guard/Reservists. These records were queried monthly to randomly select individuals for recruitment, which involved emailing a flyer with a link to a Qualtrics study screener. Follow-up telephone calls were made to enroll those interested and eligible.

Participant milestones

Participant milestones
Measure
Immediate Message Exposure
Participants complete baseline (T1), are randomized, and immediately receive 4 study videos over the first month. The exposure period ends and participants complete telephone-based assessments at 1- and 2-month follow up (T2 and T3, respectively). Study videos are delivered by the study's mobile app downloaded to the participants' own SmartPhone. Messaging: Four brief video messages that feature stories focused on the decision to seek mental health treatment.
Wait List Control Then Message Exposure at T2
Participants complete baseline and are randomized to the arm, "wait list control then message exposure at T2." While wait-listed, participants will receive one push notification each week thanking them for participation, informing them that they will receive messages in the near future or reminding them of the length of the study. Following completion of the 1-month assessment (T2), participants receive videos over 1 month period. The exposure period ends and participants complete the 2-month follow up (T3) by telephone. Videos and push notifications are delivered by study's mobile app downloaded to participants' own Smartphone.
Wait List Control Then Exposure at T3
Participants complete baseline and are randomized to the arm, "wait list control then message exposure at T3." While wait-listed, participants will receive one push notification each week thanking them for participation, informing them that they will receive messages in the near future or reminding them of the length of the study. Following completion of the 2-month assessment (T3), participants receive videos over 1 month period. The exposure period ends. There is no subsequent assessment following exposure.
Baseline (T1)
STARTED
123
116
116
Baseline (T1)
Assigned Intervention
123
0
0
Baseline (T1)
COMPLETED
123
116
116
Baseline (T1)
NOT COMPLETED
0
0
0
1-month Follow-up (T2)
STARTED
123
116
116
1-month Follow-up (T2)
Assigned Intervention
0
106
0
1-month Follow-up (T2)
COMPLETED
107
106
111
1-month Follow-up (T2)
NOT COMPLETED
16
10
5
2 Month Follow-up (T3)
STARTED
107
106
111
2 Month Follow-up (T3)
Assigned Intervention
0
0
107
2 Month Follow-up (T3)
COMPLETED
102
103
107
2 Month Follow-up (T3)
NOT COMPLETED
5
3
4
Analysis
STARTED
123
116
116
Analysis
COMPLETED
123
116
116
Analysis
NOT COMPLETED
0
0
0

Reasons for withdrawal

Reasons for withdrawal
Measure
Immediate Message Exposure
Participants complete baseline (T1), are randomized, and immediately receive 4 study videos over the first month. The exposure period ends and participants complete telephone-based assessments at 1- and 2-month follow up (T2 and T3, respectively). Study videos are delivered by the study's mobile app downloaded to the participants' own SmartPhone. Messaging: Four brief video messages that feature stories focused on the decision to seek mental health treatment.
Wait List Control Then Message Exposure at T2
Participants complete baseline and are randomized to the arm, "wait list control then message exposure at T2." While wait-listed, participants will receive one push notification each week thanking them for participation, informing them that they will receive messages in the near future or reminding them of the length of the study. Following completion of the 1-month assessment (T2), participants receive videos over 1 month period. The exposure period ends and participants complete the 2-month follow up (T3) by telephone. Videos and push notifications are delivered by study's mobile app downloaded to participants' own Smartphone.
Wait List Control Then Exposure at T3
Participants complete baseline and are randomized to the arm, "wait list control then message exposure at T3." While wait-listed, participants will receive one push notification each week thanking them for participation, informing them that they will receive messages in the near future or reminding them of the length of the study. Following completion of the 2-month assessment (T3), participants receive videos over 1 month period. The exposure period ends. There is no subsequent assessment following exposure.
1-month Follow-up (T2)
Lost to Follow-up
16
10
5
2 Month Follow-up (T3)
Lost to Follow-up
5
3
4

Baseline Characteristics

Public Messaging to Increase Treatment Seeking for Veterans at Risk for Suicide

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Immediate Message Exposure
n=123 Participants
Participants complete baseline (T1) and are randomly assigned to immediately receive 4 study videos over the first month. The exposure period ends and participants complete telephone-based assessments at 1- and 2-month follow up (T2 and T3 respectively). Study videos are delivered by study's mobile app downloaded to participants' own Smartphone. Messaging: Four brief video messages focused on facilitating treatment seeking. Intervention delivered to participant by study mobile app downloaded to participants' own smartphone.
Wait List Control Then Message Exposure at T2
n=116 Participants
Participants complete baseline and are randomly assigned to the waitlist control until receive videos at T2 (following 1-month follow up assessment). Participants receive videos over a one month period. The exposure period ends and participants complete the 2-month follow up (T3) assessment by telephone. While wait-listed, participants will receive one push notification each week thanking them for participation, informing them that they will receive messages in the near future or reminding them of the length of the study. Push notifications are delivered by study's mobile app downloaded to participants' own Smartphone. Messaging: Four brief video messages focused on facilitating treatment seeking. Intervention delivered to participant by study mobile app downloaded to participants' own smartphone. Wait list control: one push notification each week thanking individuals for participation, informing them that they will receive messages in the near future or reminding them of the length of the study.
Wait List Control Then Message Exposure at T3
n=116 Participants
Participants complete baseline and are randomly assigned to receive videos following their 2-month assessment at T3. Participants receive videos over a one month period. They are not assessed post-exposure. While wait-listed, participants will receive one push notification each week thanking them for participation, informing them that they will receive messages in the near future or reminding them of the length of the study. Push notifications are delivered by study's mobile app downloaded to participants' own Smartphone. Wait list control: one push notification each week thanking individuals for participation, informing them that they will receive messages in the near future or reminding them of the length of the study.
Total
n=355 Participants
Total of all reporting groups
Age, Continuous
34.9 years
STANDARD_DEVIATION 9.2 • n=20 Participants
36.5 years
STANDARD_DEVIATION 10.4 • n=20 Participants
37.5 years
STANDARD_DEVIATION 9.5 • n=40 Participants
36.4 years
STANDARD_DEVIATION 9.9 • n=5 Participants
Sex: Female, Male
Female
49 Participants
n=20 Participants
49 Participants
n=20 Participants
50 Participants
n=40 Participants
148 Participants
n=5 Participants
Sex: Female, Male
Male
74 Participants
n=20 Participants
67 Participants
n=20 Participants
66 Participants
n=40 Participants
207 Participants
n=5 Participants
Race/Ethnicity, Customized
White
90 Participants
n=20 Participants
79 Participants
n=20 Participants
83 Participants
n=40 Participants
252 Participants
n=5 Participants
Race/Ethnicity, Customized
Other than White
33 Participants
n=20 Participants
37 Participants
n=20 Participants
33 Participants
n=40 Participants
103 Participants
n=5 Participants
Marital Status
Never married
35 Participants
n=20 Participants
32 Participants
n=20 Participants
39 Participants
n=40 Participants
106 Participants
n=5 Participants
Marital Status
Married/cohabitating
71 Participants
n=20 Participants
64 Participants
n=20 Participants
57 Participants
n=40 Participants
192 Participants
n=5 Participants
Marital Status
Widowed/Divorced/Separated/Unknown
17 Participants
n=20 Participants
20 Participants
n=20 Participants
20 Participants
n=40 Participants
57 Participants
n=5 Participants
Education
High School/GED
38 Participants
n=20 Participants
32 Participants
n=20 Participants
32 Participants
n=40 Participants
102 Participants
n=5 Participants
Education
Undergraduate Degree
58 Participants
n=20 Participants
46 Participants
n=20 Participants
49 Participants
n=40 Participants
153 Participants
n=5 Participants
Education
Graduate Degree
27 Participants
n=20 Participants
38 Participants
n=20 Participants
35 Participants
n=40 Participants
100 Participants
n=5 Participants
Employment
Unemployed
29 Participants
n=20 Participants
28 Participants
n=20 Participants
23 Participants
n=40 Participants
80 Participants
n=5 Participants
Employment
Student
19 Participants
n=20 Participants
9 Participants
n=20 Participants
14 Participants
n=40 Participants
42 Participants
n=5 Participants
Employment
Employed
58 Participants
n=20 Participants
60 Participants
n=20 Participants
57 Participants
n=40 Participants
175 Participants
n=5 Participants
Employment
Retired
14 Participants
n=20 Participants
16 Participants
n=20 Participants
16 Participants
n=40 Participants
46 Participants
n=5 Participants
Employment
Other
3 Participants
n=20 Participants
3 Participants
n=20 Participants
6 Participants
n=40 Participants
12 Participants
n=5 Participants
Time since military separation
1 year or less
118 Participants
n=20 Participants
112 Participants
n=20 Participants
107 Participants
n=40 Participants
337 Participants
n=5 Participants
Time since military separation
2 years
4 Participants
n=20 Participants
2 Participants
n=20 Participants
6 Participants
n=40 Participants
12 Participants
n=5 Participants
Time since military separation
3 years
1 Participants
n=20 Participants
2 Participants
n=20 Participants
3 Participants
n=40 Participants
6 Participants
n=5 Participants
Rank at Separation
Enlisted
81 Participants
n=20 Participants
66 Participants
n=20 Participants
71 Participants
n=40 Participants
218 Participants
n=5 Participants
Rank at Separation
Officer
42 Participants
n=20 Participants
50 Participants
n=20 Participants
45 Participants
n=40 Participants
137 Participants
n=5 Participants
Health Insurance
Yes
106 Participants
n=20 Participants
106 Participants
n=20 Participants
111 Participants
n=40 Participants
323 Participants
n=5 Participants
Health Insurance
No
17 Participants
n=20 Participants
10 Participants
n=20 Participants
5 Participants
n=40 Participants
32 Participants
n=5 Participants

PRIMARY outcome

Timeframe: baseline through 2-month follow-up

Population: The Ns are distinct; Participants exposed at T2 contribute data as control and intervention depending on timing and outcome status (exposure is time-varying for this arm). Participants in this arm contributed data as controls (unexposed) for T1 and T2 until they received the intervention. Participants that had already experienced the outcome prior to crossover continued to contribute data as controls, whereas those who had not yet experienced the outcome were intervention observations for T3.

yes to initiating psychological treatment and/or medication/pharmacological treatment in the past month to treat mental health issues.

Outcome measures

Outcome measures
Measure
Message Exposure
n=229 Participants
the exposure group = all timepoints/participants in the "immediate exposure arm" (receive intervention following baseline) + T3 data for participants in the "waitlist then exposure at T2 arm" who had not yet initiated treatment prior to crossover.
Wait List Control
n=232 Participants
the waitlist control group = all timepoints/participants in the "waitlist then exposure at T3 arm" (received intervention at end-of-trial) + T3 data for participants in the "waitlist then exposure at T2 arm" who initiated treatment prior to crossover.
Treatment Initiation
34 Participants
19 Participants

SECONDARY outcome

Timeframe: baseline through 2-month follow up

Population: Number analyzed = the overall/final N in each condition. Given the cross-over design, participants in group 2 contribute observations to both conditions depending on timing and outcome status (exposure is time-varying for this arm).

Beliefs about mental health treatment was assessed using the "Perceptions about Services Scale" with individuals endorsing items on a scale from 1 (lowest agreement) to 7 (higher agreement). A mean is calculated across items to create a composite score (higher score = greater positive beliefs about mental health treatment); lowest score = 1; highest score = 7.

Outcome measures

Outcome measures
Measure
Message Exposure
n=229 Participants
the exposure group = all timepoints/participants in the "immediate exposure arm" (receive intervention following baseline) + T3 data for participants in the "waitlist then exposure at T2 arm" who had not yet initiated treatment prior to crossover.
Wait List Control
n=232 Participants
the waitlist control group = all timepoints/participants in the "waitlist then exposure at T3 arm" (received intervention at end-of-trial) + T3 data for participants in the "waitlist then exposure at T2 arm" who initiated treatment prior to crossover.
Mean Change in Beliefs About Mental Health Treatment
T3 (2-month follow up)
5.14 score on scale
Standard Deviation 1.50
5.16 score on scale
Standard Deviation 1.54
Mean Change in Beliefs About Mental Health Treatment
T1 (baseline)
4.51 score on scale
Standard Deviation 1.88
4.44 score on scale
Standard Deviation 1.79

SECONDARY outcome

Timeframe: baseline through 2-month follow up

Population: Number analyzed = the overall/final N in each condition. Given the cross-over design, participants in group 2 contribute observations to both conditions depending on timing and outcome status (exposure is time-varying for this arm).

change in intent to seek mental health treatment in the next month measured using a 7-point likert scale (1 indicating low intent and 7 indicating strong intent) from items in the "Perceptions about Services Scale." A mean is calculated (higher score representing higher intentions) to create a composite score on the scale. lowest score = 1; highest score = 7.

Outcome measures

Outcome measures
Measure
Message Exposure
n=229 Participants
the exposure group = all timepoints/participants in the "immediate exposure arm" (receive intervention following baseline) + T3 data for participants in the "waitlist then exposure at T2 arm" who had not yet initiated treatment prior to crossover.
Wait List Control
n=232 Participants
the waitlist control group = all timepoints/participants in the "waitlist then exposure at T3 arm" (received intervention at end-of-trial) + T3 data for participants in the "waitlist then exposure at T2 arm" who initiated treatment prior to crossover.
Mean Change in Intentions to Seek Treatment
T1 (baseline)
4.54 score on scale
Standard Deviation 2.15
4.21 score on scale
Standard Deviation 2.15
Mean Change in Intentions to Seek Treatment
T3 (2-month follow up)
4.58 score on scale
Standard Deviation 2.06
4.44 score on scale
Standard Deviation 2.07

SECONDARY outcome

Timeframe: baseline through 2-month follow up

Population: Number analyzed = the overall/final N in each condition. Given the cross-over design, participants in group 2 contribute observations to both conditions depending on timing and outcome status (exposure is time-varying for this arm).

Used the "Perceived Stigma and Barriers to Care scale" to assess change in agreement with barriers to mental health care that impede one's own behaviors measured using a response scale from 1 (strongly disagree) to 5 (strongly agree). A mean is calculated across items to create a cumulative score (higher score = more experience with barriers to care).lowest score = 1; highest score = 5.

Outcome measures

Outcome measures
Measure
Message Exposure
n=229 Participants
the exposure group = all timepoints/participants in the "immediate exposure arm" (receive intervention following baseline) + T3 data for participants in the "waitlist then exposure at T2 arm" who had not yet initiated treatment prior to crossover.
Wait List Control
n=232 Participants
the waitlist control group = all timepoints/participants in the "waitlist then exposure at T3 arm" (received intervention at end-of-trial) + T3 data for participants in the "waitlist then exposure at T2 arm" who initiated treatment prior to crossover.
Mean Change in Perceived Treatment Barriers
T1 (baseline)
2.34 score on scale
Standard Deviation 1.43
2.16 score on scale
Standard Deviation 1.36
Mean Change in Perceived Treatment Barriers
T3 (2-month follow up)
2.05 score on scale
Standard Deviation 1.27
1.94 score on scale
Standard Deviation 1.22

SECONDARY outcome

Timeframe: baseline through 2-month follow up

Population: Number analyzed = the overall/final N in each condition. Given the cross-over design, participants in group 2 contribute observations to both conditions depending on timing and outcome status (exposure is time-varying for this arm).

Items assessing subjective norms on seeking mental health care were used from "Perceptions about Services Scale" with scores ranging from 1 (low agreement) to 7 (high agreement). A mean was calculated to create a cumulative score (higher score = greater positive perceptions about seeking mental health care); 1 = lowest score; 7 = highest score.

Outcome measures

Outcome measures
Measure
Message Exposure
n=229 Participants
the exposure group = all timepoints/participants in the "immediate exposure arm" (receive intervention following baseline) + T3 data for participants in the "waitlist then exposure at T2 arm" who had not yet initiated treatment prior to crossover.
Wait List Control
n=232 Participants
the waitlist control group = all timepoints/participants in the "waitlist then exposure at T3 arm" (received intervention at end-of-trial) + T3 data for participants in the "waitlist then exposure at T2 arm" who initiated treatment prior to crossover.
Mean Change in Normative Beliefs About Seeking Mental Health Care
T1 (baseline)
5.83 score on scale
Standard Deviation 1.70
5.94 score on scale
Standard Deviation 1.71
Mean Change in Normative Beliefs About Seeking Mental Health Care
T3 (2-month follow up)
5.99 score on scale
Standard Deviation 1.44
6.03 score on scale
Standard Deviation 1.44

Adverse Events

Message Exposure

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Wait List Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Elizabeth Karras

Department of Veterans Affairs

Phone: 585-393-9350

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place