Evaluation of Sofosbuvir and Daclatasvir Combo in COIVD-19 Patients in Egypt
NCT04773756 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 54
Last updated 2021-02-26
Summary
Sofosbuvir has been recently recommended as a possible antiviral for COVID-19, based on structural studies and multiple alignment analysis. By comparing the positive-stranded RNA genomes of HCV and SARS-CoV-2, it has been postulated that sofosbuvir might be an optimal nucleotide analogue to repurpose for COVID-19 treatment
Conditions
- Covid19
Interventions
- DRUG
-
Sofosbuvir 400 MG/ Daclatasvir 60mg
Giving these two drugs for treatment of COVID patients
Sponsors & Collaborators
-
Alexandria University
lead OTHER
Principal Investigators
-
Amr Abd elmoety, PhD · Alexandria University, Faculty of Medicine
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 12 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-11-01
- Primary Completion
- 2020-11-30
- Completion
- 2020-12-12
- FDA Drug
- Yes
Countries
- Egypt
Study Locations
More Related Trials
-
Sofosbuvir/Ledipasvir and Nitazoxanide for Treatment of COVID-19
NCT04498936 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Favipiravir in Management of COVID-19
NCT04349241 ·Status: COMPLETED ·Phase: PHASE3
-
Levamisole and Isoprinosine in the Treatment of COVID19: A Proposed Therapeutic Trial
NCT04383717 ·Status: UNKNOWN ·Phase: PHASE3
-
Efficacy and Safety of Sirolimus in COVID-19 Infection
NCT04461340 ·Status: UNKNOWN ·Phase: PHASE2
-
Comparison of Remdesivir Versus Lopinavir/ Ritonavir and Remdesivir Combination in COVID-19 Patients
NCT04738045 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy of Faviprevir in COVID-19 Treatment
NCT04351295 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
New Antiviral Drugs for Treatment of COVID-19
NCT04392427 ·Status: UNKNOWN ·Phase: PHASE3
-
Hydroxychloroquine and Nitazoxanide Combination Therapy for COVID-19
NCT04361318 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Ivermectin and Nitazoxanide Combination Therapy for COVID-19
NCT04360356 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Remdesivir in Adults With Covid-19: Mansoura University Hospital Experience
NCT04728880 ·Status: UNKNOWN
-
Ivermectin In Treatment of COVID 19 Patients
NCT04425707 ·Status: UNKNOWN ·Phase: NA
-
Novel Regimens in COVID-19 Treatment
NCT04382846 ·Status: RECRUITING ·Phase: PHASE3
-
Comparison of Tocilizumab Versus Tocilizumab/Infliximab in Patients With COVID-19-associated Cytokine Storm Syndrome
NCT04734678 ·Status: COMPLETED
-
Comparative Therapeutic Efficacy and Safety of Different Antiviral and Anti Inflammatory Drugs in COVID-19 Patients.
NCT04779047 ·Status: UNKNOWN ·Phase: PHASE4
-
Levamisole and Isoprinosine in Immune-prophylaxis of Egyptian Healthcare Workers Facing COVID-19
NCT04360122 ·Status: UNKNOWN ·Phase: PHASE3
-
A Randomized Controlled Trial to Investigate The Role of Adjuvant Inhalable Sodium Bicarbonate Solution 8.4% in Treatment of COVID-19
NCT05035524 ·Status: UNKNOWN ·Phase: NA
-
Remdesivir Efficacy In Management Of COVID-19 Patients
NCT04853901 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Alisporivir for the Treatment of Hospitalised Patients With Infections Due to SARS-CoV-2 (COVID-19)
NCT04608214 ·Status: COMPLETED ·Phase: PHASE2
-
Prevention and Treatment for COVID -19 (Severe Acute Respiratory Syndrome Coronavirus 2 SARS-CoV-2) Associated Severe Pneumonia in the Gambia
NCT04703608 ·Status: UNKNOWN ·Phase: PHASE3
-
Remdesivir Efficacy in Coronavirus Disease
NCT04345419 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Ivermectin Role in Covid-19 Clinical Trial
NCT04746365 ·Status: COMPLETED ·Phase: PHASE4
-
Antiviral Agents Against COVID-19 Infection
NCT04468087 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
The Efficacy of Ivermectin in Larger Doses in COVID-19 Treatment
NCT04351347 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 Pandemic
NCT04668469 ·Status: COMPLETED ·Phase: NA
-
Persistence of Symptoms After Improvement of Acute COVID-19
NCT04764773 ·Status: COMPLETED