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Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients

NCT04770363 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2023-03-27

No results posted yet for this study

Summary

This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.

Conditions

  • Stroke, Ischemic
  • Stroke, Acute
  • Stroke, Lacunar
  • Hemiparesis
  • Hemiplegia
  • Motor Activity
  • Spastic
  • Spasticity, Muscle
  • Hemiplegic Gait

Interventions

DEVICE

Transcranial Direct Current Stimulation (tDCS)

Transcranial direct current stimulation (tDCS) is an emerging non-invasive brain stimulation technique which has been utilized in examining cortical function in healthy subjects and also showed significant outcome in neurological rehabilitation. A safe, portable, noninvasive painless, reversible, selective and focal brain stimulation technique, applied by sponge electrodes over the scalp. tDCS is capable of modulating the excitability of targeted brain zones through delivering a sustained direct current (DC), showed altering neuronal membrane potentials based on the polarity of the current. Researchers demonstrated modulating effects of anodal (increases cortical excitability) and cathodal (decreases cortical excitability) tDCS on brain tissue. The expected effects of tDCS brain stimulation exceeds the duration. Animal studies showed neuronal depolarization and increasing neuronal excitability of the anodal stimulation, and opposite results with cathodal stimulation.

Sponsors & Collaborators

  • Alexandria University

    lead OTHER

Principal Investigators

  • Nema Mohamed, PHD Prof · Faculty of Science - Alexandria University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-02-01
Primary Completion
2021-05-30
Completion
2021-06-20
FDA Device
Yes

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04770363 on ClinicalTrials.gov