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Prehospital Management of Hypotensive Trauma in HEMS

NCT04760977 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2024-08-13

No results posted yet for this study

Summary

Up to today, inadequate evidences and knowledge exist about the best prehospital management of hypotensive trauma patients and its clinical consequence on the in-hospital recovery and mortality.

Also new emerging therapies such as prehospital blood transfusion and REBOA (resuscitative endovascular balloon occlusion of the aorta) are lacking strong evidences in, eventually, reducing hospital mortality and improving outcomes.

Moreover, prehospital emergency medicine is throughout Italy an heterogeneous system that has no unique standard operating procedures and, even among HEMS (helicopter emergency medical service), management and therapies on complex trauma patients may vary upon local policies.

With this study we aim to enroll hypotensive trauma patients and study factors of prehospital rescue that can be associated with in-hospital mortality and recovery, eventually even with hospital outcome. For each patients data as demographic, kind of trauma (mechanism, injury scores), therapies and maneuvers will be recorded and then analyzed in comparison with in-hospital data such as need for transfusion, ABG parameters, length of stay (in-ward and ICU), need of therapies like invasive ventilation and renal replacement therapy, recovery and outcome

Conditions

  • Hypotension and Shock
  • Wounds and Injuries
  • Emergencies
  • Critical Care

Interventions

DRUG

Drugs administration

Antifibrinolytics, analgesics, sedatives, neuromuscular blocking agents

DEVICE

Resuscitative endovascular balloon occlusion of the aorta

Resuscitative technique for exsanguinating traumas

BIOLOGICAL

Blood transfusions

Transfuion of transported blood products for exsanguinating traumas

OTHER

Prehospital management

Stay and play strategy vs scoop and run

DEVICE

Prehospital eFAST

Prehospital thorax/abdomen extended focused assessment sonography for trauma

Sponsors & Collaborators

  • Azienda Usl di Bologna

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-01
Primary Completion
2025-05-01
Completion
2026-05-01

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04760977 on ClinicalTrials.gov