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Malic Acid in Treatment of Xerostomia

NCT04756986 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2021-02-16

No results posted yet for this study

Summary

Background: xerostomia is a subjective sensation of dry mouth resulting from quantitative and /or qualitative changes of saliva. Patients receiving drugs like antihypertensives and antidepressants or patients receiving chemotherapy or radiotherapy for treatment of head and neck cancers may suffer from xerostomia. It also can be experienced in patients with systemic diseases like diabetes mellitus, systemic lupus erythematosus, sjogren's syndrome and rheumatoid arthritis. Malic acid spray with concentration of 1% has grabbed the attention over the last few years as an effective treatment for xerostomia.

Study objective: To evaluate the effect of 1% malic acid spray in treatment of xerostomia in type 2 diabetic patients.

Conditions

  • Xerostomia

Interventions

DRUG

malic acid

1% malic acid spray

Sponsors & Collaborators

  • Hams Hamed Abdelrahman

    lead OTHER

Principal Investigators

  • Eglal M Mousa, PHD · Alexandria University

  • Yasmin Y Gaweesh., PHD · Alexandria University

  • Noha K. Abo Aasy, PHD · Alexandria University

  • Shaimaa A. Muhamed, BDS · Alexandria University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2021-09-01
Completion
2021-11-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04756986 on ClinicalTrials.gov