MedTrace Logo

Eye Gaze Strategies During Facial Emotion Recognition in Neurodegenerative Diseases: Links With Neuropsychiatric Disorders (EYE-ToM Study)

NCT04748263 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 74

Last updated 2026-05-08

No results posted yet for this study

Summary

It is commonly admitted that social cognition impairment, like deficit in facial emotion recognition or misinterpretation of others' intentions (Theory of Mind), are associated with social behavior disorders.

This kind of disorders are observed in Fronto-Temporal Dementia (FTD), Alzheimer's Dementia (AD) and Parkinson's Disease (PD), with severe deficits in FTD and lighter deficits in AD and PD.

One explanation might be that patients apply inappropriate visual exploration strategies to decode emotions and intentions of others.

This study aims to test this hypothesis and further to analyse whether different patterns emerge from these pathologies.

Conditions

  • Alzheimer's Dementia
  • Parkinson Disease(PD)
  • Fronto-Temporal Dementia

Interventions

OTHER

No intervention. Only survey and normal use of eye-tracking

The study is conducted in accordance with usual practices of eye-tracking and neuropsychological evaluations carried out at the Center Rainier III. Eye-Tracker® is used at the Centre Rainier III since August 2014. It is a non-invasive device for eye movements recording, allowing doctors and researchers to measure standard parameters related to eye movements. Developed by the Eye Brain Company (France), this is a Class IIa medical device, CE marking, according to Annexe IX of the directive 93/42/CE.

Sponsors & Collaborators

  • Association de Recherche Bibliographique pour les Neurosciences

    collaborator OTHER

  • Centre Hospitalier Princesse Grace

    lead OTHER

Principal Investigators

  • Alain PESCE, MD-PHD · CH Princesse Grace

  • Sandrine LOUCHART de la CHAPELLE, MD · CH Princesse Grace

Eligibility

Min Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-07-01
Primary Completion
2019-12-01
Completion
2020-11-01

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04748263 on ClinicalTrials.gov