MedTrace Logo

Effects of Peripherally Acting µ-opioid Receptor Antagonists on Acute Pancreatitis

NCT04743570 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 105

Last updated 2023-04-21

No results posted yet for this study

Summary

This study will investigate the effect of peripheral acting opioid antagonist (PAMORA) on the disease course of patients with acute inflammation of the pancreas (acute pancreatitis). The study will be conducted by treating hospitalized patients with acute pancreatitis with a PAMORA (methylnaltrexone).

Conditions

Interventions

DRUG

Placebo treatment

Active drug/placebo is given for the first 5 days of admission.

DRUG

Methylnaltrexone treatment

Active drug/placebo is given for the first 5 days of admission.

Sponsors & Collaborators

  • Odense University Hospital

    collaborator OTHER

  • Hvidovre University Hospital

    collaborator OTHER

  • University Hospital Bispebjerg and Frederiksberg

    collaborator OTHER

  • Asbjørn Mohr Drewes

    lead OTHER

Principal Investigators

  • Asbjørn M. Drewes, Professor · Mech-Sense, Department of Medical Gastroenterology, Aalborg Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-14
Primary Completion
2023-04-09
Completion
2023-04-20

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04743570 on ClinicalTrials.gov