Trial Outcomes & Findings for Perimodiolar Implant Performance in Adults With Low-Frequency Residual Hearing (NCT NCT04741009)

NCT ID: NCT04741009

Last Updated: 2026-08-17

Results Overview

To characterize hearing performance of the CI632 using the Consonant-Nucleus-Consonant (CNC) monosyllabic word recognition test in quiet (unilateral). Two CNC word lists will be administered at a level equal to 60 dBA in the sound field and scored as a total number of words correct, expressed as a percentage correct.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

10 participants

Primary outcome timeframe

14 months (12 months postactivation)

Results posted on

2026-08-17

Participant Flow

Participant milestones

Participant milestones
Measure
CI632 Slim Modiolar Electrode
The Cochlear Ltd CI632 cochlear implant with Slim Modiolar Electrode
Overall Study
STARTED
10
Overall Study
COMPLETED
9
Overall Study
NOT COMPLETED
1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Perimodiolar Implant Performance in Adults With Low-Frequency Residual Hearing

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
All Participants
n=10 Participants
The Cochlear Ltd CI632 cochlear implant with Slim Modiolar Electrode
Age, Continuous
61.3 years
STANDARD_DEVIATION 9.8 • n=51 Participants
Sex: Female, Male
Female
8 Participants
n=51 Participants
Sex: Female, Male
Male
2 Participants
n=51 Participants
Race/Ethnicity, Customized
White
10 Participants
n=51 Participants
Race/Ethnicity, Customized
Non-Hispanic
10 Participants
n=51 Participants
Region of Enrollment
United States
10 Participants
n=51 Participants

PRIMARY outcome

Timeframe: 14 months (12 months postactivation)

To characterize hearing performance of the CI632 using the Consonant-Nucleus-Consonant (CNC) monosyllabic word recognition test in quiet (unilateral). Two CNC word lists will be administered at a level equal to 60 dBA in the sound field and scored as a total number of words correct, expressed as a percentage correct.

Outcome measures

Outcome measures
Measure
All Participants
n=9 Participants
The Cochlear Ltd CI632 cochlear implant with Slim Modiolar Electrode
To Characterize Hearing Performance of the CI632 in an Adult Population Under Expanded Indications for Use.
79.1 Percentage of words correct
Standard Deviation 5.8

Adverse Events

All Participants

Serious events: 0 serious events
Other events: 7 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
All Participants
n=10 participants at risk
The Cochlear Ltd CI632 cochlear implant with Slim Modiolar Electrode
Ear and labyrinth disorders
Ear infection
10.0%
1/10 • 12 months
General disorders
Pain
10.0%
1/10 • 12 months
Nervous system disorders
Taste disorder
10.0%
1/10 • 12 months
Ear and labyrinth disorders
Tinnitus
20.0%
2/10 • 12 months
Nervous system disorders
Headache
10.0%
1/10 • 12 months
Nervous system disorders
Numbness
10.0%
1/10 • 12 months
Skin and subcutaneous tissue disorders
Blister
10.0%
1/10 • 12 months
Ear and labyrinth disorders
Vertigo
10.0%
1/10 • 12 months
Ear and labyrinth disorders
Aural fullness
10.0%
1/10 • 12 months
General disorders
High blood pressure/ hypertension
10.0%
1/10 • 12 months
Ear and labyrinth disorders
Ear pain
10.0%
1/10 • 12 months
Nervous system disorders
Balance problems
10.0%
1/10 • 12 months

Additional Information

PRS Specialist

Cochlear Limited

Phone: +61 2 9428 6555

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place