To Evaluate the Efficacy and Safety of Micafungin in Preventing Invasive Mycosis After Liver Transplantation
NCT04728971 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 200
Last updated 2022-08-16
Summary
To evaluate the clinical success rate of micafungin in preventing invasive mycosis after liver transplantation.
Conditions
- Liver Transplantation
Interventions
- DRUG
-
Micafungin Sodium 50 MG Injection
Give Micafungin 150 mg/d within 24 hours after liver transplantation.
- DRUG
-
Caspofungin Acetate
Give Caspofungin 35 mg/d lasts 1 week after liver transplantation.
Sponsors & Collaborators
-
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 60 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-10-01
- Primary Completion
- 2025-10-01
- Completion
- 2026-02-01
More Related Trials
-
Anidulafungin Versus Fluconazole for the Prevention of Fungal Infections in Liver Transplant Recipients
NCT00841971 ·Status: COMPLETED ·Phase: PHASE4
-
Caspofungin as Prophylaxis in High Risk Liver Transplantation Recipients
NCT01260974 ·Status: UNKNOWN ·Phase: PHASE2
-
A Retrospective Study Evaluating the Efficacy and Safety of Micafungin Sodium in the Treatment of Invasive Fungal Infections
NCT02678598 ·Status: COMPLETED
-
Study of Micafungin in Patients With Invasive Candidiasis or Candidemia
NCT00105144 ·Status: COMPLETED ·Phase: PHASE3
-
Micafungin Prevention Study for Invasive Fungal Disease in Pediatric & Adolescent Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation
NCT01417169 ·Status: UNKNOWN ·Phase: PHASE2
-
Prophylaxis With Caspofungin in High-Risk Liver Transplantation
NCT00333645 ·Status: UNKNOWN ·Phase: PHASE2
-
Post Marketing Study to Evaluate the Efficacy and Safety of Micafungin Treatment on Invasive Aspergillosis
NCT02646774 ·Status: TERMINATED ·Phase: PHASE4
-
A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults (MK-0991-066)
NCT00635648 ·Status: COMPLETED ·Phase: PHASE3
-
Micafungin Versus Fluconazole in the Treatment of Invasive Candidiasis and Candidemia
NCT00189709 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluate Bioequivalence of Micafungin (50mg/Vial)
NCT05496725 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Two Treatments to Prevent Invasive Fungal Infections in Patients Who Have Received Liver Transplants
NCT00001107 ·Status: COMPLETED ·Phase: PHASE4
-
Micafungin Prevention Study for Fungal Disease in Child Receiving Allogenic Hematopoietic Stem Cell Transplantation
NCT01135589 ·Status: UNKNOWN ·Phase: PHASE4
-
A Study to Evaluate Pre-emptive Treatment for Invasive Candidiasis in High Risk Surgical Subjects
NCT01122368 ·Status: COMPLETED ·Phase: PHASE2
-
Comparative Study of Micafungin (FK463) Versus Placebo as Prophylactic Antifungal Therapy in the ICU
NCT00048750 ·Status: TERMINATED ·Phase: PHASE3
-
Micafungin Salvage Mono-therapy in Invasive Aspergillosis
NCT00376337 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Safety and Pharmacokinetics of Repeated Dose of Micafungin as Antifungal Prophylaxis in Children and Adolescents Who Undergo Hematopoietic Stem Cell Transplant
NCT00606268 ·Status: COMPLETED ·Phase: PHASE1
-
Micafungin Versus AmBisome in Invasive Candidiasis and Candidemia
NCT00106288 ·Status: COMPLETED ·Phase: PHASE3
-
A Clinical Study on the Efficacy and Safety of ABCD in the Treatment of Patients With Invasive Fungal Disease
NCT06376201 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Micafungin Versus Intravenous Itraconazole as Empirical Antifungal Therapy for Febrile Neutropenic Patients With Hematological Diseases
NCT01344681 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation
NCT04368559 ·Status: COMPLETED ·Phase: PHASE3
-
Short and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents
NCT01686607 ·Status: COMPLETED
-
Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis
NCT00665639 ·Status: COMPLETED ·Phase: PHASE3
-
Pharmacokinetics of Micafungin in Patients of Intensive Care Units
NCT02164890 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Systematic Therapy and Bronchoscopic Interventional Treatment for Pulmonary Mucormycosis
NCT06495905 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.
NCT06925321 ·Status: RECRUITING ·Phase: PHASE3