MedTrace Logo

The Incidence of Complete Posterior Vitreous Degeneration After Phacoemulsification

NCT04727398 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 92

Last updated 2023-10-10

No results posted yet for this study

Summary

Intraocular surgery could induce vitreous degeneration and then abnormal posterior vitreous detachment (PVD) could occur including vitreoschisis and partial-thickness PVD. Vitreomacular interface (VMI) abnormalities such as epimacular membrane were observed following many intraocular surgeries. The incidence of peripheral break and epimacular membrane (EMM) after pneumatic retinopexy were 11.7% and 4-11%, respectively. Although multiple intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections induced PVD of 5.6%, but peripheral break was reported as only 0.67%. The incidence of rhegmatogenous retinal detachment (RRD) after phacoemulsification is gradually increased with time. The accumulative risk of RRD was increased from 0.27% at 1 year to 1.27% at 20 years after phacoemulsification.

Conditions

  • Posterior Vitreous Detachment

Interventions

DEVICE

Wide-field optical coherence tomography (Optovue®)

Merged 4 images for wide-filed OCT-based PVD classification, 2 vertical line images and 2 horizontal line images

Sponsors & Collaborators

  • Khon Kaen University

    lead OTHER

Principal Investigators

  • Suthasinee Sinawat, MD · KKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-03
Primary Completion
2024-12-30
Completion
2025-06-30

Countries

  • Thailand

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04727398 on ClinicalTrials.gov