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Efficacy of Placebo Versus Chlorpheniramine for the Prevention of Allergic Transfusion Reactions.

NCT04688736 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 6642

Last updated 2025-08-05

No results posted yet for this study

Summary

This is a prospective, randomized, double-blind controlled trial to evaluate the efficacy of placebo versus chlorpheniramine for the prevention of allergic transfusion reactions.

Conditions

  • Allergic Transfusion Reaction

Interventions

DRUG

Placebo

The tablet resembles chlorpheniramine but has no therapeutic value.

DRUG

Chlorpheniramine

An antihistamine that reduces the natural chemical histamine in the body.

Sponsors & Collaborators

  • Institute of Hematology & Blood Diseases Hospital, China

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2026-12-31
Completion
2027-06-30

Countries

  • China

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04688736 on ClinicalTrials.gov