Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies
NCT04672434 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2024-12-09
Summary
The primary purpose of this study is to see if Sym024 is safe and tolerable as monotherapy and in combination with Sym021 in patients with solid tumor malignancies.
Conditions
Interventions
- DRUG
-
Sym021
Sym021 is a humanized anti-PD-1 antibody.
- DRUG
-
Sym024
Sym024 is an anti-CD73 antibody.
Sponsors & Collaborators
-
Symphogen A/S
lead INDUSTRY
Principal Investigators
-
N. Lakhani, MD PhD · START Midwest, USA
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-11-19
- Primary Completion
- 2024-11-22
- Completion
- 2024-11-22
- FDA Drug
- Yes
Countries
- United States
- Canada
Study Locations
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